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Biomedical subjects

P C Muzzio

Publications and source records attributed to P C Muzzio.

At least 19 recordsLinked to original sources
PubMed1992

Adjustable silicone gastric banding for obesity.

Adjustable gastric banding is the least invasive operation for morbid obesity. Forty-eight patients underwent surgical adjustable gastric banding between March 1990 and August 1991. In 15 of these patients, radiological examination was performed in the early postoperative period because of dysphagia and vomiting, revealing stenosis of the stoma in all cases (caliber less than 0.3 cm); in all patients we easily punched, with fluoroscopically guided observation, the inflatable portion and obtained a true calibration of the gastric banding. In seven patients radiological examination was performed 2 months after surgical treatment because of a lack of weight loss. Radiological findings explain surgical failure, revealing a too wide stoma in four patients, the absence of a gastric pouch due to a too high position of the band in two, and the caudal sliding of the banding in one patient.

Adult↗
PubMed1992

[A comparison between echography and computed tomography in assessing neoplastic recurrences in superficial soft tissues].

Thirty-seven superficial soft-tissue recurrences were evaluated with ultrasonography (US) and computed tomography (CT) to assess the correct diagnostic approach. US and CT examinations were performed at the same time. High-frequency US probes and a third-generation CT scanner were employed; all the lesions underwent also histology or cytology. US correctly identified as recurrences or fibrous tissue all the 37 lesions, whereas CT diagnosed 30 lesions only. Seven of the 14 recurrences < 2 cm diameter were not demonstrated. In conclusion, US provides more reliable information than CT relative to small lesions, which suggests that US must be performed just after therapy. Nevertheless, when bone involvement is suspected, CT is required and its use is also suggested to monitor distant metastases.

Biopsy, Needle↗
PubMed1992

[The T1 time dependence of water measured in normal and neoplastic lung tissues].

The authors determined the time dependence of the average T1 relaxation time for the constitutive water of normal and neoplastic lung tissues. In healthy tissues, the T1 dependence appears strictly as a single decaying exponential function down to a threshold value which is invariant over time. The time change of T1 in neoplastic tissues is represented by monoexponential functions, in the short and long run, with a sudden drop 2 weeks after beginning measurements. Moreover, the time dependence is independent of the examined variant of epidermoid carcinoma. We report the kinetic constants of the in vitro aging of the tissues. The presence of a cooperative process, involving neoplastic lung water, to explain the features of aging changes, is also suggested.

Aged↗
PubMed1991

[The proton relaxation times in normal and neoplastic thyroid tissue. An in vitro study].

Aim of the work is the in vitro evaluation of normal and tumoral thyroid tissue relaxation times, in order to obtain useful information for MR Imaging in vivo. Water proton high-resolution MR spectra, together with T1 and T2 relaxation times, have been measured in normal and tumoral thyroid tissues. The longitudinal relaxation time T1 was particularly sensitive to pathologic tissue: significant differences (mean: 243 ms) were observed between normal and tumoral tissues, which is a useful finding for the successful application of MR techniques to the detection of tumors in the thyroid gland. The average T1 relaxation time, for each class of examined tumors, correlates qualitatively with the degree of malignancy. On the contrary, the transverse relaxation time T2 was insensitive to pathologic changes in the tissues. The analysis of water proton spectra showed the overall Free Induction Decay constant T2 to allow an easier discrimination than T2 between normal and pathologic thyroid tissue. Thus, T1-weighted sequences probably provide better discrimination than T2-weighted scans in the evaluation of normal and tumoral thyroid tissues.

Adult↗
PubMed1991

[Measurement of gastric emptying with Tc 99m. Technique and reliability of the test].

Among the various methods used to measure gastric emptying time, scintigraphy is nowadays the technique of choice. Since only few data are available on the operative characteristics of the method, the authors investigated reproducibility, sensitivity, and specificity of a modified scintigraphic technique for the measurement of gastric emptying time. Three groups of subjects--healthy volunteers, patients with functional dyspepsia, and patients with upper gastrointestinal conditions--were administered liquid meals having various standard consistencies (349 tests on the whole). In both healthy volunteers and dyspeptic patients the method had high sensitivity (72%), good specificity (69%), and low intra-subject variation (25%). In all cases, the increase in meal density produced a delay in gastric emptying. Dyspeptic patients had slow gastric emptying of high-fiber meals, while in duodenal ulcer and in atrophic gastritis emptying was significantly faster. The radionuclide method proved valuable in measuring gastric emptying and was useful to confirm the pathogenesis of the various conditions. As for functional and organic pathologic conditions, it allowed treatment efficacy to be evaluated.

Adult↗
PubMed1991

Elastofibroma: CT and MR findings.

Two cases of elastofibroma of the chest wall are reported. Each patient was investigated with CT and, in 1 case, MR imaging was also performed. Elastofibroma appears like a mass in the subscapular region and often presents problems of differential diagnosis. The contribution of MR imaging is reported.

Adult↗
PubMed1988

Pancreatic cancer: CT scan.

The results of 72 cases of histologically confirmed pancreatic neoplasm are reviewed. By applying a semeiological scheme, which considers intra and extrapancreatic alterations, it is shown that the possibility of a pre-invasive diagnosis on CT is still limited, and requires further confirmation. CT examination is unique for demonstrating the extension of the lesion, and provides truly probative findings for a specific diagnosis, especially when signs of direct local or distant invasion appear.

False Negative Reactions↗
PubMed1988

Pancreatic carcinoma, diagnostic ERCP.

Fifty-three patients underwent endoscopic retrograde cholangiopancreatography (ERCP). Thirty-eight patients had pancreatic disease, diagnosed on the basis of surgical and/or instrumental-clinical findings, and consisted of 17 cases of carcinoma (group A), 10 cases of chronic pancreatitis with benign stenosis of the pancreatic duct (group B), and 11 cases of chronic pancreatitis without stenosis (group C). Linear discriminant analysis was employed to evaluate differential diagnosis data relative to secondary pancreatic ducts. With this method, 16/17 patients (94%) were correctly assigned to group A (high sensitivity), 7/8 patients (88%) to group B, and 7/10 patients (70%) to group C. A readily found radiological sign, such as abrupt and/or irregular stenosis of the pancreatic duct enables the correct diagnosis of carcinoma, but while this criterion is highly specific, it is poorly sensitive. If a clearly neoplastic stenosis of the main duct is not present, an analysis of the secondary ducts is determinant.

Cholangiopancreatography, Endoscopic Retrograde↗
PubMed1988

[Radiologic diagnosis of anal fistulae with radio-opaque markers].

Fistulography classifies anal fistulas in low-below puborectalis muscle-, high-above puborectalis muscle-, and middle. This classification increases the scope and accuracy of radical surgery. In order to improve the diagnostic reliability of anal fistulography the authors point out the importance of radio-opaque markers for anatomical definition of the anorectal region. Thirty patients (25 males and 5 females; mean age: 47 years) were studied by anal fistulography using radiopaque markers: a Foley's 22 Fr catheter, with distal balloon filled of idrosoluble radiopaque contrast medium, was placed in the anal canal; a metal marker was fixed to the anus. In order to demonstrate the relationship between fistula and puborectalis muscle, we subdivided the anal canal in 3 equal segments: high, middle and low. The idrosoluble contrast medium for fistulography is injected through a pediatric Foley's catheter 8 Fr when external opening is large enough, and through a K7072 endovenous catheter when the opening is small. Fistulous tract was visible in all patients: internal fistulous opening in 23/90 cases, and relationship of fistulous tract to puborectalis muscle in 25/30 (83.3%). In demonstrating either secondary fistulous tracts or abscesses, fistulography with radiopaque markers was correct in 60% of cases; in 20% of patients some of the above-mentioned complications were demonstrated, and in the 20% no complications at all were detected.

Adult↗
PubMed1987

[Behavior of T1 relaxation time in normal and neoplastic pulmonary tissue. An in vitro study].

The aim of the study was to look for a difference between normal and neoplastic lung tissue by means of Magnetic Resonance Spectroscopy in vitro. A 2.1 Tesla intensity spectrometer was used. From 23 pneumonectomized patients, two samples from the lung were taken immediately after surgery: one from the center of the neoplasm, one from the healthy surrounding tissue; on each of them T1 relaxation time was measured. Twenty patients out of 23 had a higher T1 relaxation time in the pathologic tissue than in the healthy surrounding tissue; only in 3 cases the T1 of neoplastic tissue was lower than that of the healthy tissue. A correlation was also sought between the T1 value and the histologic type of the neoplasm. In epidermoid carcinoma, the T1 relaxation time increased with the malignity of the neoplasm.

Adenocarcinoma↗
PubMed1986

[Duodenal and colonic involvement in neoplastic pathology. Anatomical and radiological considerations].

The authors present 3 cases of duodeno-colic involvement by malignant neoplasms and analyse the main radiological features. Benign and malignant duodenocolic fistulas are discussed and colic lesions caused by an extrinsic process. Guiding radioanatomical criteria are stated namely the alterations in the site of the principal lesion first and, afterwards, the morphological changes or displacement of the bowel.

Adenocarcinoma↗
PubMed1986

[Radiologic methods in the evaluation of upper esophagoplasties].

Post-operative radiologic control of esophageal plastic surgical procedures in pathologic conditions of the cervical esophagus involves difficulties due to the poor collaboration of the patient, who swallows only small quantities of contrast medium. Contrast medium injection through esophageal-gastric probes, and its reflux toward the cervical region with the Trendelemburg position and/or straining, enables the demonstration of fistulas otherwise unrecognized.

Administration, Oral↗
PubMed1985

[Radiological and instrumental study of the colon in idiopathic constipation].

It has been demonstrated that it is not always possible to attribute to constipation a reduced colonic transit time as being evidenced by radiological studies using radiopaque markers. In fact, in constipated patients with a normal transit time, it was more reasonable to consider a recto-anal disorder as evidenced by defecography and manometry.

Anus Diseases↗
PubMed1979

[Multi-institution, multidisciplinary radiology and endoscopy trial of the diagnostic accuracy of the double contrast examination of the stomach surface].

In 12 X-ray and gastroenterology departments 1570 patients, clinically suspected to have a gastric pathology, have been examined by double contrast (surface) examination of the stomach followed by gastroscopy. Diagnostic accuracy was 93% in respect of endoscopic data, assumed correct by hypothesis. On the basis of a cost and benefit evaluation, made according to the well known criteria, a wider routine use of the double contrast technique is proposed.

Adolescent↗
PubMed1979

[New radiological aspects of the intestinal mucosa in celiac sprue: injection of barium into the intestinal glands].

The radiologic findings are described of mucosal folds thickening in coeliac sprue in patients with short clinical history. Moreover attention is pointed on the flattening of the valves and the thinning of the intestinal walls which appear in dilated segments in cases with evident clinical findings. Finally in patients with long standing clinical manifestations and histologic positive controls, a thin spiculation of intestinal outlines and a dotted mucosal surface are visible, probably due to the filling of the Lieberkühn glands with contrast medium.

Barium Sulfate↗