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Biomedical subjects

P C Reade

Publications and source records attributed to P C Reade.

At least 163 records · Page 9Linked to original sources
PubMed1978

Changes in the activity of the reticulo-endothelial system of rats during an infection with T. lewisi.

Data presented show that during the course of a Trypanosoma lewisi infection in rats there was both an activation of the phagocytic cells of the liver and spleen and an increase in their numbers. There was a marked lymphoid hyperplasia in the white pulp of the spleen with an increase in the number and size of the lymphoid follicles. Degenerative changes occurred in the liver parenchymal cells during the infection, and at certain stages large numgers of mononuclear cells were observed in the vascular sinusoids and other vessels of the liver.

Animals↗
PubMed1978

Transplantation of bovine odontogenic tissues and dissociated odontogenic cells to hypothymic mice.

It was demonstrated in this study that bovine odontogenic tissues and the dissociated cell preparations of such tissues, when transplated to the subcapsular kidney site of hypothymic mice, retained their phenotypic expression and continued function to produce their recognisable products, dentine and enamel matrices. It was also shown that in the grafts of dissociated odontogenic tissues, cell sorting occurred so that histotypical tissues were formed and that their function produced readily recognisable dentine and enamel matrices. Attention has been drawn to the usefulness of this model for studying a variety of events that occur during odontogenesis.

Animals↗
PubMed1978

In vitro studies on the use of cetylpyridinium chloride as a bacterial plaque control agent.

Studies have shown that cetylpyridinium chloride (CPC) containing mouthwash may in vitro inhibit artificial bacterial plaque accumulation under certain conditions. These studies, together with the findings of clinical trials, suggest that the clinical activity of CPC in partially limiting plaque accumulation depends on its adherence to cleaned enamel surfaces rather than its penetration in performed plaque.

Adsorption↗
PubMed1977

Oro-facial pain.

Oro-facial pain is commonly acute, and of dental origin. There are numerous other less common, but clinically identifiable types of oro-facial pain which can be attributed to an organic cause, and which usually respond to the appropriate treatment. There is a small proportion of oro-facial pain problems, however, which are chronic and which are found to have a psychogenic element of greater or lesser magnitude, and treatment is aimed at psychological or psychiatric therapy. The interim results of an ongoing study of chronic oro-facial pain of psychogenic origin are described in this presentation.

Adolescent↗
PubMed1977

Oral medicine.

Explore the source record for details and available documents.

Candidiasis, Oral↗
PubMed1976

Torulopsis glabrata infection in the oral cavity.

The first case report of an oral infection due to Torulopsis glabrata is presented. This microorganism is a yeast-like fungus grouped in a similar family to the Candida species. It has been isolated with increasing frequency from the oral cavity but, surprisingly, has not been reported as a pathogen in this site. In other anatomical sites, including the urinary tract, lung and gastrointestinal tract, Torulopsis glabrata has been reported as a pathogen, at times resulting in a fatal outcome. However, there has usually been some modifying factor, e.g. malignancy, cytotoxic drug therapy, diabetes or broad spectrum antibiotics, which caused this marginal pathogen to assume a pathogenic role. No such modifying factors could be elicited in this case. The history of the case including the management is presented. A brief outline of the microbiologic grouping of Torulopsis glabrata is given, as well as the diagnostic test used in its identification. The histopathology is described and the necessity for combining special tests in establishing a positive diagnosis is exemplified, as the histology alone is not pathognomonic of the infection.

Candida↗
PubMed1976

The effects of tobacco smoking on oral and dental tissues.

An attempt has been made in this paper to review the clinical problem of the effects of tobacco smoking on oral and dental tissues. Clinicians are alerted to the magnitude of the problem and to its serious sequelae. An appeal is made for clinicians to disseminate preventive information, to exercise increased clinical vigilance and to consider the management of suspected neoplastic lesions as emergency situations.

Adult↗
PubMed1976

Suppression of immune responsiveness by a submandibular salivary gland factor.

Both tissue extracts prepared from submandibular salivary glands of male mice and epidermal growth factor isolated from these glands depressed the delayed type hypersensitivity response to 2,4-dinitro-1-fluorobenzene in mice. Extirpation of the submandibular salivary glands from male mice did not alter the delayed type hypersensitivity response. The role of salivary gland factors, particularly epidermal growth factor, in influencing the immune response has been discussed.

Animals↗