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Biomedical subjects

P C Reynolds

Publications and source records attributed to P C Reynolds.

At least 19 recordsLinked to original sources

Adapting the Ohmeda UPAC draw-over vaporizer for use in the modern operating room.

Until recently, the use of draw-over anesthesia (DA) for elective cases has been prohibited in American military hospitals. The reasons cited for this have included the possibility of increased patient risk and the delivery of a second level of care. In this article, the authors outline a method of employing DA so as to bring its use up to the safety level of the modern operating room. This allows for the clinical training of those military anesthesia care providers who may find themselves deployed with highly mobile surgical units whose missions demand this technique of anesthesia.

Anesthesia, Inhalation

Cocaine-related death.

Cocaine use and abuse, an ancient custom, is once again commonplace. While severe toxicity appears to be rare, overt poisoning including death can occur. This report documents nine cases of death associated with cocaine use; in three of these cocaine appears to be causative. Toxicologic analysis of body fluids and tissues was affirmative and levels are reported. Cocaine should be considered in serious drug overdose-reactions, especially after illicit injection.

Adolescent

Postmortem tissue methamphetamine concentrations following selegiline administration.

Selegiline is a relatively new antiparkinson's drug whose metabolites include methamphetamine and amphetamine. A 72-year-old female with apparently suicidal intentions was found dead at her residence. The cause of death was listed as coronary heart disease with a history of polypharmacy. The tissue methamphetamine and amphetamine concentrations resulting from selegiline administration are presented in this report.

Aged

Fetal and newborn death associated with maternal cocaine use.

Data collected from 25 cases of fetal or newborn death associated with maternal cocaine use are reported. The average week of gestation at which fetal death occurred was week 30. Abruptio placentae was observed in 7 cases and placental infarct was found in 4 cases. The average fetal blood cocaine and benzoylecgonine levels were 0.26 and 1.73 micrograms/mL. The average maternal levels were 0.14 and 1.80 micrograms/mL, respectively.

Cocaine