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Biomedical subjects

P C Tillman

Publications and source records attributed to P C Tillman.

6 recordsLinked to original sources
PubMed1983

Medical and surgical management of gastric obstruction from a hairball in the rabbit.

Gastric hairballs in a colony of mature laboratory rabbits were associated with chronic, partial, or complete gastric obstruction and inanition. Clinical signs included anorexia, decreased fecal output, weight loss, and depression. The differentiation of anorexia induced by hairballs, stress, and other causes presented a diagnostic dilemma. Radiographs could not be relied upon to differentiate gastric hairballs from normal gastric contents. Combined medical and surgical management optimized successful recovery. Supportive therapy was given 12 to 24 hours before surgical removal of the hairball and was continued postoperatively for 72 hours.

Animals↗
PubMed1983

Noninvasive observations of fluorinated anesthetics in rabbit brain by fluorine-19 nuclear magnetic resonance.

Fluorinated anesthetics were observed noninvasively in the brain of intact rabbits with fluorine-19 nuclear magnetic resonance spectroscopy. High-resolution fluorine-19 spectra of halothane, methoxyflurane, and isoflurane were obtained with a surface coil centered over the calvarium. Elimination of halothane from the brain was also monitored by this technique. Residual fluorine-19 signals from halothane (or a metabolite) could be detected as long as 98 hours after termination of anesthesia. These observations demonstrate the feasibility of using this technique to study the fate of fluorinated anesthetics in live mammals.

Animals↗
PubMed1983

Sonographically guided percutaneous cholecystostomy performed in dogs and pigs.

An ultrasound-guided percutaneous cholecystostomy was attempted in six dogs and seven pigs. The pig was a more suitable laboratory animal since the biliary anatomy of swine is similar to that of humans; the anteriorly located gallbladder was ideal for puncture. Use of a single-stick catheter was preferable to a guidewire exchange technique.

Animals↗
PubMed1983

A rapid method for devocalizing goats.

Goats were devocalized electrosurgically through the oral cavity. Special methods were necessary due to the small size of the caprine vocal folds and their distance from the commissures of the mouth. The vocal folds were difficult to visualize and beyond the reach of the instruments usually used for ventriculochordectomy in dogs. The use of a specially designed ovine laryngoscope blade and a 38-cm electrode made it possible to devocalize goats under ketamine-xylazine anesthesia quickly and noninvasively. No tissue was removed. The electrode was placed over the vocal folds, and the current was applied briefly. Animals so treated have not been observed to recover their voices after 4 to 18 months of observation postsurgically.

Animals↗
PubMed1982

Group G streptococcal epizootic in a closed cat colony.

An epizootic of beta-hemolytic Lancefield group G streptococcal infections occurred in a specific-pathogen-free colony of laboratory cats. A total of 19 out of 68 animals in a single building were affected over a 10-day period. Clinical signs included fever, depression, lymphadenopathy, pharyngitis, and submandibular edema. The organism was recovered from the pharynx in two of five clinically normal cats from the affected building. Cultures from 12 animals in the same colony but housed in unaffected buildings were negative. Two doses of long-acting penicillin G 72 h apart stopped the outbreak and resulted in negative cultures for previously affected animals. Three months later, two new cases occurred in the same building. The disease was finally eradicated from the colony by depopulating the affected building.

Animals↗