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P C Vijn

Publications and source records attributed to P C Vijn.

5 recordsLinked to original sources

Topography of occipital EEG-reduction upon visual stimulation.

Visual stimuli were designed to drive a high proportion of the neurons in restricted parts of the human visual cortex. These stimuli were used to examine changes in the ongoing EEG during visual stimulation. The topographic organization of these changes was studied. It was found that the EEG from those parts of the cortex that are exposed to the stimulus is strongly reduced in amplitude. This stimulus dependency is indicative that cortical processing results itself in a reduction of the ongoing EEG, presumably due to desynchronization of neurons. The method shows that ongoing EEG can be used for functional mapping of cortical areas and is therefore valuable in situations where stimulus locked activity can not be measured.

Brain Mapping

A random dipole model for spontaneous brain activity.

The statistical properties of the EEG and the MEG are described mathematically as the result of randomly distributed dipoles. These dipoles represent the interactions of cortical neurons. For certain dipole distributions, the first- and second-order moments of the electric and magnetic fields are derived analytically. If the dipoles are in a spherical volume conductor and have no preference for any direction, the variance of a differentially measured EEG-signal is only a function of the electrode distance. In this paper, the theoretically derived variance function will be compared with EEG- and MEG-measurements. It is shown that a dipole with a fixed position and a randomly fluctuating amplitude is an adequate model for the alpha-rhythm. An expression for the covariance between the magnetic field and a differentially measured EEG-signal is derived. This covariance is considered as a function of the magnetometer position, and is compared with the measurements of Chapman et al. [23]. The theory can be used to obtain a (spatial) covariance matrix of the background noise, which occurs in evoked potential measurements. Such a covariance matrix can be used to obtain a maximum likelihood estimator of the dipole parameters in evoked potential studies, to evaluate the merits of the so-called "Laplacian derivation," and for the interpolation of electromagnetic data.

Artifacts

Visual stimulation reduces EEG activity in man.

Data are presented which show that background electric activity of the human brain is reduced by visual stimulation. Occipital EEG amplitude decreases 5-15% for all frequencies analyzed (0.2-40 Hz) upon pattern stimulation. The reduction is stimulus-specific, i.e. is the strongest for stimuli that activate a large number of visual cortical neurons.

Electroencephalography

A practical method for determining electrode positions on the head.

When multi-channel EP recordings are used for source localization, the electrode positions have to be determined with respect to a common reference frame. In this paper a method is described for determining the electrode positions on the head. Since it is difficult to fix electrodes accurately at a priori chosen positions, it is better to measure these positions afterwards. For this we have developed a practical method. The method also finds the best fitting sphere for the electrode position, which is useful when a multi-sphere volume conductor is used in the inverse algorithm.

Algorithms