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Biomedical subjects

P Calderoni

Publications and source records attributed to P Calderoni.

At least 37 records · Page 2Linked to original sources
PubMed1983

Maffucci's syndrome. Report of 3 cases and review of the literature.

Maffucci's syndrome is a rare condition which is not hereditary. It is manifested by multiple chondromata associated with subcutaneous angiomata. Up to now only 109 cases have been reported in the literature. Malignant degeneration is reported in about 15% of cases. The authors present 3 more cases, in one of which sarcomatous degeneration occurred in one of the chondromata.

Adolescent↗
PubMed1983

[A very frequent radiologic sign in dorsolumbar localization of chordoma: increase in the interpeduncular distance].

The X-ray picture of 11 cases of chordoma of the thoraco-lumbar spine at the Tumors Centre of the Rizzoli Orthopaedic Institute is studied. In 7 cases an increase in the interpeduncular distance of the affected vertebrae was noticed. The high incidence of this radiologic sign, never reported previously in the literature, represents a semeiologic element of great importance in the diagnosis of this neoplasm. The ways of measurement are then indicated and the significance of this report is stressed.

Chordoma↗
PubMed1983

Intracapsular metaphyseal osteoid osteoma of the femoral neck.

The authors discuss the 20 cases of intracapsular metaphyseal osteoid osteoma of the neck of the femur found among the total 186 cases of osteoid osteoma on the files of the Tumour Centre of the Rizzoli Orthopaedic Institute. They assess the diagnostic methods that can be used to determine the precise position of the "nidus" with reference to the surgical route to be used. The operation must expose the osteoid osteoma directly by opening the joint.

Adolescent↗
PubMed1982

Solitary plasmacytoma of the vertebral column. A report of 15 cases.

The clinical features and the treatment results of 15 patients with solitary plasmacytoma of the spine observed in a 28-year period (1950-1977) are reported. The signs at presentation were back pain in 4 cases and spinal cord compression in 11 cases. Three of these patients had paraplegia. Radiologically, the alteration encountered was an osteolytic lesion in all cases. The local treatment was radiotherapy in 11 cases and surgery plus radiotherapy in 4 cases. In 3 patients systemic chemotherapy was also employed. Seven patients are alive without signs of disease 3 to 9 years (mean 6 years) after diagnosis. Eight patients developed multiple myeloma in a period ranging from 1 to 8 years (mean 3.5 years). The relationship between multiple myeloma and solitary plasmacytoma of the spine, as well as the best treatment for the latter, are discussed.

Adult↗
PubMed1982

Full-lung tomograms and bone scanning in the initial work-up of patients with osteogenic sarcoma. A review of 126 cases.

The value of full-lung tomograms and of bone scanning in the initial work-up of patients with osteogenic sarcoma is evaluated in 126 consecutive cases observed at the Bone Tumor Center of the Istituto Ortopedico Rizzoli from July 1976 to December 1980. Full-lung tomograms and bone scanning showed unsuspected metastases in 3 patients and 2 patients respectively. False abnormal results were observed in 4 cases by tomography and in 3 cases by bone scan. The authors conclude that in osteosarcoma, the yields of full-lung tomography and of bone scanning are small in detecting unsuspected lung and bone metastases at the time of presentation. It therefore appears improbable that the improvements recently observed in this tumor with adjuvant chemotherapy are the result of unintentional case selection bias due to these examinations not having been performed in the historical group.

Adolescent↗
PubMed1982

Primary non-Hodgkin's lymphoma of bone: results in 15 patients treated by radiotherapy combined with systemic chemotherapy.

The authors report on the results obtained in 15 patients with primary non-Hodgkin's lymphoma (NHL) of bone treated by radiotherapy and polychemotherapy; 86% of the patients (13 of 15) were continuously disease-free at a median follow-up of 70 months (42-104). No local recurrence was observed. The necessity of clearly distinguishing primary non-Hodgkin's lymphoma of bone from Ewing's sarcoma is discussed.

Adolescent↗
PubMed1981

Estimation of gestational age during the first trimester by real-time measurement of fetal crown-rump length and biparietal diameter.

A series of 237 patients in the first trimester of pregnancy were examined to derive normal growth curves for fetal crown-rump length (CRL) and biparietal diameter (BPD) using sector scanner real-time ultrasound equipment. Conventional B-scan CRL measurements were obtained from 50 of these patients: In 41 (82%), the values fell within a range +/- 5 mm of those of real-time. Another group of 97 patients between 7 and 13 wk of gestation was then examined in a blind trial to confirm the accuracy of real-time measurements in estimating gestational age. An estimate was made in 95% of cases to within 4.6 days with CRL and to within 5 days with BPD. A similar comparison was made with both of these dimensions using a comparative nomogram, giving a prediction within 3.9 days in 95% of cases. This method is now used routinely.

Anthropometry↗
PubMedDate not supplied

Loss of bone mass after total hip replacement: preliminary data.

In a total of 37 females with cemented total hip replacement for monolateral coxarthrosis, of which 13 with prosthetic stem loosening, and 11 with monolateral coxarthrosis that is not prosthetized, bone mineral density (BMD) is determined by dual ray photonic absorbimetry selecting regions of interest (ROI) on the cortex of the femurs 4 cm under the lesser trochanter and on the ischium bilaterally. In females that are not prosthetized there are differences in bone mass between the two femurs and the ischium on both sides. In prosthetized patients BMD of the femur and of the ischium on the side operated on is significantly less than on the contralateral one (Student's "t" test: p < 0.001). In patients with stable prostheses, BMD of the femur operated on is greater than that in females with prosthetic stem loosening (Student's "t" test: p < 0.000). Based on a comparison between these two groups we did not observe any other significant differences in BMD among the ROI analyzed. BMD was correlated with the amount of time since surgery only in the ROIs in prosthetized femurs. The study confirms the significant bone resorption of the cortex in prosthetized femurs and documents analogously significant reduction in BMD in the ischium on the side operated on. Finally, it indicates that prosthetic stem loosening may be associated with loss of BMD in the femoral cortex which is significantly greater than that observed, during analogous periods of time in stable implants.

Aged↗
PubMedDate not supplied

Hip arthroplasty in coxarthrosis secondary to Paget's disease.

A total of 5 hip arthroplasties implanted between 1997 and 2000 in 5 patients affected with coxarthrosis secondary to Paget's disease were reviewed. The quality of the pagetic bone (sclerotic and very vascularized) resulted in a slightly longer amount of time required for surgery because of the difficulty preparing prosthetic placement and intra- and postoperative blood loss exceeding the norm. Complications were not observed. Clinical results were good in 100% of cases. Radiographically, 2 stems were assembled in varus.

Aged↗
PubMedDate not supplied

Hip prosthesis revisions with LS stem: indications and results.

The authors present a study that includes 350 patients affected with loosening of hip arthroplasty and submitted to revision with a Wagner LS stem at the 4th Division of the Rizzoli Orthopaedic Institute. Several different types of cotyle (Fitek, Wagner, Standard Cup, cemented cotyle with support ring, Octopus system) were used depending on the anatomopathologic findings, combined with autoplastic grafts. Staging and grading of loosening were based on the four G.I.R. grades. A clinical evaluation of results was based on the Merle D'Aubigné parameters modified by Charnley. For radiographic evaluation the De Lee Charnley areas were studied for cotyle, the Gruen areas for the femoral stem. Overall, good results were obtained in 175 patients, fair in 137, poor in 38.

Adult↗
PubMedDate not supplied

Autologous chondrocytes implantation: indications and results in the treatment of articular cartilage lesions of the knee.

Articular cartilage lesions of the knee constitute a frequent event and one that is difficult to treat. In time, different surgical methods have been used with results that are often contradictory. The authors report the indications and results of different methods used in the treatment of cartilage lesions: in particular, the experience initiated in 1997 with autologous chondrocytes implantation is discussed. Between 1997 and 2000, a total of 40 patients were submitted to autologous chondrocytes implantation injected in suspension under a periosteal flap. This method includes wide exposure of the joint lesion by arthrotomy. Between 1999 and 2001, a total of 30 patients were submitted to autologous chondrocytes implantation using a tridimensional matrix. The availability of biomaterial simplified the implant method and made arthroscopy possible. All of the patients were submitted to serial clinical follow-ups. MRI was also conducted for a second arthroscopic look. The results obtained in both series after a mean follow-up of 4 years (range 2 to 6 years) are good, and confirm the effectiveness of the method that allows for complete morphological and structural repair of lesions of the joint cartilage.

Adolescent↗
PubMedDate not supplied

Glomus tumor in children (description of one case).

Glomus tumor is a lesion of the soft tissues which rarely occurs in children. One case of the disease characterized by deep localization and atypical radiographic symptoms and manifestations is described.

Child↗