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Biomedical subjects

P Calloway

Publications and source records attributed to P Calloway.

6 recordsLinked to original sources

The association of education and socioeconomic status with the Mini Mental State Examination and the clinical diagnosis of dementia in elderly people.

The distribution of scores in the Mini Mental State Examination (MMSE) of women aged 70-79 years from a rural area of Cambridgeshire is reported. Increasing age, lower socioeconomic group and less education were all found to be associated with lower scores on MMSE. Of these, only increasing age was significantly related to an increase in the diagnosis of dementia.

Aged

Serum creatine kinase BB isoenzyme levels in an epidemiological study of dementia and cognitive impairment.

It has been suggested that serum creatine kinase levels might be useful in the investigation of dementia. In this study serum creatine kinase BB (CKBB) isoenzyme levels were investigated in a community population of elderly women aged 70 to 80 years. Normative data for this group were compared with the findings in younger age groups. No relationship was found between levels of CKBB and level of dementia, or with the specific clinical diagnosis of senile dementia of the Alzheimer type, although a weakly positive relationship was found between CKBB and 3 cognitive scales.

Age Factors

An epidemiological study of dementia in a rural population of elderly women.

A study of 365 women aged 70-79 in a rural community was carried out using the Cambridge Examination of Mental Disorders in the Elderly (CAMDEX). Prevalence rates of dementia are reported by severity for the 70-74 and 75-79 age groups. Differential diagnosis was made according to CAMDEX guidelines. Senile dementia of Alzheimer type accounted for half the dementia cases. The prevalence rates overall did not differ from those reported in other recent studies, but the rates for levels greater than mild/moderate were lower, despite the inclusion of subjects in institutions.

Aged

Normal ageing, impaired cognitive function, and senile dementia of the Alzheimer's type: a continuum?

There is little evidence to support the view that senile dementia of the Alzheimer's type (SDAT) is distinct from the normal ageing process. The changes in brain function found in normal ageing, benign senescent forgetfulness, and SDAT can be seen as a continuum, which may reflect a single underlying process. The failure to account for this possibility in research design may explain why few risk factors for SDAT have been identified.

Age Factors