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Biomedical subjects

P Cappelletti

Publications and source records attributed to P Cappelletti.

28 records · Page 2Linked to original sources

Clinical chemical indexes and severity of coronary atherosclerosis.

The present study measured triglycerides (TG), total cholesterol (TC), HDL-cholesterol (HDL-C), LDL and LDL/HDL-C, TC/HDL-C and HDL-C/TC. 100 ratios in 261 men and women undergoing coronary arteriography. The results show that TG, TC, HDL-C and LDL levels are not related to the severity of coronary artery disease (CAD). The LDL/HDL-C, TC/HDL-C and HDL/TC.100 ratios are statistically related to the severity of CAD. The LDL/HDL-C ratio appeared to be the most sensitive index for reflecting CAD of mild severity with a predictive value of 83.3% at 76.6% specificity and at 77.7% sensitivity (cut-off: 3.20). Average values of LDL and HDL-C alone are not reliable indices of mild severity CAD.

Adult↗

[Serum viscosity and chronic hepatopathies].

In 26 patients with chronic liver disease, the serum viscosity was studied. In 42% of subjects, the serum viscosity was found increased, almost always associated with clinical findings of central nervous system involvement. The remission of central nervous system symptoms occurs with fall into normal range of serum viscosity levels. Therefore, the serum hyperviscosity should be included among various causes of cirrhosis encephalopathy. When serum viscosity is increased, relates rather to immunoglobulins (IgG, IgA, IgM) increases then to increased amounts of total globulins.

Adolescent↗

Effects of posture on plasma and serum viscosity.

This study demonstrates the importance of defining normal reference population ranges for P- and S-viscosity with respect to posture. The normal ranges determined for P-viscosity are not acceptable as a reference range for a hospitalized population that is predominantly in a supine position. Mean percentage changes of P- and S-viscosity in the recumbent posture as compared to the same population in the upright posture were 7.51 and 5.88, respectively.

Adult↗

Alpha-naphthyl butyrate esterase (a selective cytochemical monocyte marker).

This paper describes a cytochemical technique for alpha-naphthyl butyrate esterase demonstration in monocytes obtained from peripheral blood of normal subjects, of a patient with reactive monocytosis and of a patient with myelomonocytic leukemia. It utilizes pH 6.1 alpha-naphthyl butyrate as substrate. At this pH value, alpha-naphthyl butyrate is a specific monocyte marker. The cytochemical procedure proposed is simple, rapid and standardized, as it utilizes stable and easily available reagents.

Carboxylic Ester Hydrolases↗