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Biomedical subjects

P Carlino

Publications and source records attributed to P Carlino.

9 recordsLinked to original sources

[Antifungal varnish in the treatment of denture stomatitis].

The efficacy of a single-dose application of miconazole varnish in the treatment of denture stomatitis was compared with miconazole gel applied three times/day for 15 days. Among 288 wearers of complete dentures 50 patients severely affected by denture stomatitis and heavily colonized by Candida, were selected. The patients were assigned randomly to two groups: a miconazole varnish group and a gel group. All patients were examined 7 times: before starting the treatment (day 0); during treatment (day 3, 7 and 14); after treatment (day 21, 28 and 35). At each examination a photograph of the palatal mucosa was obtained and quantitative cultures of Candida from the lesions and the fitting denture surface were performed. At day 14 the inflammation was reduced to the same degree in the two groups of patients. A comparison of the antifungal effect, i.e. reduction of the yeast score, showed no significant difference between the two groups. Maximum reduction of the number of yeasts was obtained at day 14. From that moment, recolonization started; thus, about 60% of the treated patients whether it was with the gel or the varnish was positive of Candida by day 35. In conclusion, the present study showed no difference in the clinical and antifungal effect of a single-dose application of miconazole varnish compared with miconazole gel. The varnish seemed to be better with respect to the posology as the total dose of miconazole is minimal and only one application is necessary. Treatment with the miconazole varnish seems particularly indicated in debilitated and non-cooperative patients suffering from Candida-associated denture stomatitis.

Administration, Topical

[Lichen planus. Clinical diagnosis, epidemiology and pathogenesis].

Lichen planus is a common mucocutaneous disease of unknown etiology which was initially described a century ago. The specific etiology remains unclear. A number of relationships between lichen planus and other conditions have been noted. The lesions occur most commonly on the buccal mucosa. Gingival involvement occurs in approximately 10% of reported cases. The appearance of lichen planus is extremely variable which leads to confusion with other clinically similar disease entities.

Adult

[Focal epithelial hyperplasia].

Five cases of "focal epithelial hyperplasia" (FEH) of the oral mucosa observed in Switzerland are reported. The patients were of Turkish and North African extraction. The lesions of FEH were multiple, painless, located at various sites of the oral mucosa including the tongue in the form of either soft papules or hard nodules. Evidence of a human papilloma virus origin was ascertained. Among the 1067 cases reported in the literature and reviewed for this study, this condition has been described to occur among American Indians, Eskimos and North African, also in Israeli and European cases the disorder was often reported in individuals of Turkish or North African extraction.

Adult

[Myxoma of the jaws].

A review of the literature and two observations made by the Authors regarding maxillary myxoma allow a closer analysis to be made of this rare benign tumour which is, however, often recurrent in young adults. Maxillary myxoma is identified by the appearance of a non-inflammatory and often painless swelling which, in radiological terms, appears to have a zone of multilocular and sometimes unilocular osteolysis. In histological terms, this globular whitish-greyish gelatine-like tumour is made up of an abundant stroma which encloses star-shaped or fusiform cells and rare collagen fibres. Treatment should be conservative where possible since radical surgery does not preclude recurrence; follow-up should be regular and long in order to ensure an early diagnosis of recividation. Although it is considered an odontogenic tumour, the odontogenic nature of maxillary myxoma has not been undisputably ascertained. The term maxillary myxoma is therefore preferable to that of odontogenic myxoma.

Adult

[Intramandibular inclusions of salivary gland tissue].

Salivary gland tissue inclusions in the mandible appear as well delimited radiolucency areas, asymptomatic, usually located in the mandibular angle and sometimes in the premolar canine and symphysis regions. The examination of 8,500 radiographs has demonstrated an incidence of one radiolucent area at the mandibular angle every 500 radiographs. Our result is slightly inferior to the mean reported in the literature. Seven cases were examined. Six of them have been treated surgically and histologically. At exploration a defect in the lingual cortical plate was found. The cavities were filled by salivary gland tissue. The contents of the cavities were attached via the lingual cortical defect to the near salivary gland. The cause of such radiolucency situated in the mandibular angle seems to be an altered resorption and apposition process of the bone triggered by a modification of the salivary glands elasticity; on the contrary, the salivary inclusions in the symphysis region is referred to as embryonic origin. In the literature different terms are used often in relation with a pathogenetical hypothesis; in this paper we suggest rather a description terminology such as intramandibular salivary tissue.

Adult

The effect of verbal commitment and treatment choice on medication compliance in a pediatric setting.

This experiment examined the manner in which verbal commitment and treatment choice affect medication compliance in a pediatric setting. Parents (N = 89) of children suffering from an inner ear infection (otitis media) were asked or not asked for a verbal promise to give their child all prescribed antibiotic medication (commitment manipulation) and allowed or not allowed to choose between two equally appropriate antibiotics as the treatment for their child (choice manipulation). Self-reports at follow-up visits, which were supported by urinalysis results, indicated that obtaining a verbal commitment significantly increased medication compliance. Verbal commitment also nonsignificantly increased the likelihood of a resolved infection at follow-up. Providing the parent with a choice of treatments had no effect on compliance or health outcome.

Adolescent

[Psychogenic oral paresthesia].

Psychogenic oral paresthesia represent a proteiform condition, more and more frequent. The failure to recognize it can lead to unjustified investigations or/and procedures. These manifestations are secondary to a psychic problem which varies in severity. In most cases, the establishment of a trust relationship, explanations to the patient and eventually a psychotherapy are sufficient to eliminate the symptoms. In severe cases, a psychotherapy or a psychiatric treatment are almost always necessary.

Adult