PubMed Health⌕ Search

Biomedical subjects

P Charlet

Publications and source records attributed to P Charlet.

8 recordsLinked to original sources

[Effectiveness of the Cell Saver and salvage from ultrafiltered extracorporeal circulation in heart surgery].

The efficiency of two intraoperative techniques of blood saving were compared prospectively. During a period of eight months, in 120 adults patients undergoing heart surgery with a cardiopulmonary bypass (CPB). They all had blood removed before the start of CPB for isovolaemic haemodilution. They were randomly assigned to two groups (n = 60 for each): for group A patients, blood was salvaged during surgery before the start of the CPB, during cardioplegia, and from the CPB circuit at the end of surgery, using a Cell Saver 1V (Haemonetics), and returned to the patient in theatre or in intensive care; in group B patients, blood in the CPB circuit at the end of surgery was ultrafiltered and returned to the patient at the same time as 0.8 mg.kg-1 protamine sulfate. The same anaesthetic protocol was used in all the patients (flunitrazepam, phenoperidine and pancuronium bromide). There was no significant difference between the two groups in the volume of blood removed at the start of surgery (9.12 +/- 2.01 ml.kg-1 (A) vs. 8.85.2.22 ml.kg-1 (B)), in the amounts of replacement fluid (Haemaccel, 4% albumin) given to maintain volaemia, and in postoperative blood loss Red cell count, haemoglobin level and haematocrit were higher in the Cell Saver group at the third postoperative hour and on the first postoperative day, whereas fibrinogen levels and platelet count were higher in the ultrafiltration group at the same times. A mean of 1.02 +/- 1.71 homologous blood units were given to group A and 1.45 +/- 1.71 in group B (not significant).(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

[Comparative trials of fluid gelatins on hemostasis in heart surgery in adults].

The purpose of this study was to compare, in adult cardiac surgery, the results of two gelatin substitutes (Plasmion and Haemaccel) especially for haemostasis and coagulation factors. Patients showing before operation any perturbation of blood parameters (anaemia, coagulation troubles) as well as patients suffering from serious complications or deceased in the postoperative period have been excluded. This study was realised with 54 patients randomised in two groups: group P (Plasmion); group H (Haemaccel). Anaesthesia was a diazanalgesia. Hemodilution was used in combination with autologous peroperative blood transfusion and reinfusion of residual blood from ECC after ultrafiltration. The two groups were statistically similar. In average, patients received the same gelatins quantity. The only remarkable findings were: a lesser decrease of platelets number per-ECC: a lesser fibrinogen level in postoperative period with Haemaccel.

Aged↗

[The use of the Haemolite Cell Saver in cardiovascular surgery].

In eighteen adult patients scheduled for cardiac and vascular surgery, shed blood was treated with the Haemonetics Cell Saver Haemolite. On average by patient, the autologous blood volume restored was 471.94 +/- 235.7 ml. The haemoglobin level was 16.88 g.dl-1 and haematocrit level was 49.31 +/- 7.2%. Thirteen by eighteen patients did not require any homologous blood transfusion. The Cell Saver Haemolite technique is restricted to moderate and gradual peroperative bleeding. This technique is particularly designed for vascular and pediatric surgery. Postoperative shed blood salvage is a marginal indication.

Adult↗

[Oral treatment of acute infantile diarrhoea with sucrose/electrolyte solution (author's transl)].

The value of oral re-hydratation in acute diarrhoea has been demonstrated in a study of 161 infants (mean age 6.8 months, range 1 to 26 months). One litre of solution contained sodium 50 mEq, potassium 25 mEq, bicarbonate 2 g, glucose 20 g, sucrose 20 g with an osmolarity of 300 milliosmoles/kg. Using this solution, rapid replacement of water osses was possible. Dehydratation, the major complication of acute diarrhoea, was thereby prevented and treated without the use of parenteral therapy. However parenteral treatment is still necessary in severe cases (shock, acidosis or severe diarrhoea).

Acute Disease↗