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P Couderc

Publications and source records attributed to P Couderc.

At least 109 records · Page 6Linked to original sources

[Renaut's bodies and familial neuropathy of the Dejerine-Sottas type. Apropos of 2 anatomo-clinical cases].

The authors report the pathological and clinical findings in two cases of familial Dejerine-Sottas neuropathy, including the peripheral nerve lesions of an unusual type producing extensive sub-perineural separation. In one case, there was onion bulb hypertrophy of the schwann layer and definite demyelinisation and above all, endoneural nodular structures known as Renaut bodies. The presence of Renaut bodies has not, to our knowledge, yet been reported in Dejerine-Sotta's disease. It is rare but well known during other neural diseases, which are often familial and in various pathological circumstances, such as syringomylia, diabetes and hypothyroidism. The fibroblastic origin of these structures has been proved. Their possible pathogenic role and their significance are still the object of discussion.

Adolescent↗

[Analysis of loco-regional control rate, metastatic remission and survival in 178 breast cancer patients treated by radical modified mastectomy and post-operative irradiation (author's transl)].

178 cases of post-operative irradiation for breast cancer (145 T1, T2, T3 and 33 T4) are analyzed. According to the surgical procedure there are 146 cases of radical modified mastectomy (Patey) and 32 cases of radical mastectomy (Halsted). The axillary status reveals 50% of involved nodes, but radiotherapy has been systematic on chest wall and supra-clavicular, parasternal, axillary lymph nodes areas. Loco-regional failures are only situated on chest wall (3,9%) and in the supraclavicular area (1,7%). The five year actuarial rate of locoregional control is 93% and 98% if we exclude 7 locoregional failures contemporaneous or consecutive to a metastatic evolution. The five year actuarial rate of metastatic remission for patients with negative axillary nodes (N-) is 83% against 55% for N+ (p < 0,001). The five year actuarial survival rate is 92% (N-) and 64% (N+) (p < 0,001). We discuss about indications of selective irradiation of chest wall and parasternal area for patients with negative axillary nodes and also about post-operative immuno-suppression, and chronology of chemotherapy.

Adult↗

[Collar-stud tumour composed of combined neurilemmona and haemangioma elements. Clinicopathological study of one case with mediastinal and intraspinal localization (author's transl)].

A mediastinal and intraspinal collar-stud tumour in a 77 year-old-woman is reported. The orginality of this study comes from the histologic findings of a combined neurilemmoma and angioma. The authors also include a brief review of literature and clinicopathological and histogenetic comments, about these combined tumours.

Aged↗

[Detection of glial fibrillary acidic protein in central nervous tumors using an immunohistochemical method. Preliminary study of 33 cases (author's transl)].

Thirty-two cases of human central nervous tumor and one experimental glioma were studied in fixed paraffin or epon embedded tissues using the peroxidase-antiperoxidase method. The present study confirms the usefulness of immunohistochemical methods for the diagnostic evaluation of neuro-epithelial neoplasms. The authors also include some prognostic and histogenetic comments about glial tumors.

Glial Fibrillary Acidic Protein↗