Biomedical subjects
P D Challen
Publications and source records attributed to P D Challen.
Intra-venous sedation.
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General anaesthesia--who decides and why?
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The continuing saga of piped medical gas supply.
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Intra-aortic balloon counterpulsation. Clinical experience.
From March 1975 until September 1978, seventy patients were referred for intra-aortic balloon counterpulsation for cardiogenic shock complicating acute myocardial infarction or for the treatment of low cardiac output states following cardiopulmonary bypass. Sixty of these received adequate intra-aortic balloon pump assistance; fifty-two ped successfully off the balloon pump. Twenty-three patients survived to leave hospital.
0.125% bupivacaine for obstetric analgesia?
A prospective trial was designed to assess the effectiveness of three different concentrations of bupivacaine (Marcain) for use in obstetric epidural analgesia. The purpose of the study was to see if reduction of the concentration of bupivacaine to 0.125% would reduce the total dose of the drug given without reducing the efficiency of the epidural block. The concentrations studies were 0.125%, 0.25% and 0.375%. The trial was limited to fit primiparous patients at term with singleton pregnancies and vertex presentation. Patients with intercurrent medical disease or with toxaemia were excluded. A total of ninety-three patients were studied, and once admitted to the trial they were randomly allocated to one of the three concentrations. In general the results of the trial show that 0.125% bupivacaine had a significantly higher failure rate than either of the other two concentrations, but in those cases where 0.125% was effective and achieved total pain relief there was a significant reduction in the amount of the drug used.
Unexplained death during anaesthesia.
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Buried alive. Some fresh air for the conscious patient under towels.
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The use of neuroleptanalgesia during surgery for phaeochromocytoma. Reports of two cases.
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Whither or wither.
I have been involved in general anaesthesia in general dental practice for almost 25 years and have always been concerned that there appears to be a lower standard when compared with hospital anaesthesia. The reasons for this are historical, political, and financial.