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Biomedical subjects

P D Sponseller

Publications and source records attributed to P D Sponseller.

At least 73 records · Page 4Linked to original sources
PubMed1991

Anterior innominate osteotomies for failure or late closure of bladder exstrophy.

The bony pelvis was analyzed in 12 patients undergoing a further operation after initial bladder closure. Of the patients 5 had undergone a prior posterior osteotomy. All patients had wide diastasis of the pubis (average 5.5 cm.). In 9 of these patients late closure or reclosure of a failed initial bladder repair was done and 3 underwent a repeat bladder neck reconstruction. In all patients a new procedure, anterior iliac osteotomy with internal or external fixation, was performed. This procedure provides increased mobility of the pubis and increased correction. It avoids turning of the patient while under anesthesia for repeat preparation and in most cases postoperative traction is not needed. There were no instances of dehiscence, nonunion or infection. Three cases of transient femoral palsy were noted. All patients had a normal gait 4 months postoperatively. The mobility obtained after anterior osteotomy allows for excellent approximation. In view of evidence that approximation of the pubis improves closure and eventual continence results, we believe that osteotomies, even when repeated, are useful in revision surgery if there is bony diastasis.

Bladder Exstrophy↗
PubMed1991

Skeletal involvement in children who have chronic granulomatous disease.

Chronic granulomatous disease is a rare disorder of the oxidative metabolism of the white blood cells that results in immunodeficiency. In a retrospective review of the records of forty-two patients who had chronic granulomatous disease, we identified thirteen patients who had a total of twenty skeletal infections. Two types of infection were noted: Type 1, which resulted from a direct spread of the infection from an adjacent focus, usually of fungus or mycobacteria, and Type 2, which resulted from hematogenous spread, usually of Nocardia or more common bacteria. The thoracic vertebrae, ribs, and metatarsals were the most commonly involved bones. All four patients in whom the vertebrae were involved had a Type-1 fungal infection. Paresis developed in three of these patients, and two of them died. Antibiotics alone effectively eradicated the infection in only one patient. Wide operative débridement combined with administration of antibiotics was the most successful treatment. Comprehensive preoperative imaging and several cultures are necessary to locate the infection in the bone and to identify the organism.

Adolescent↗
PubMed1990

Open fractures of the tibia in children.

Forty-one children who had forty-two open fractures of the tibial metaphysis or diaphysis were studied retrospectively. Twelve fractures were Type I; eighteen, Type II; six, Type IIIA; four, Type IIIB; and two, Type IIIC, according to the classification of Gustilo et al. All fractures were irrigated and debrided, and antibiotics were given for a minimum of forty-eight hours after the injury. Twenty fractures were initially treated with external fixation and twenty-two, with immobilization in a plaster cast. Three patients had an early infection of the wound, one of which was associated with osteomyelitis; all were successfully treated. The average time to healing of the fracture was five months (range, two to twenty-one months). The time to union was related to the severity of the soft-tissue injury, the pattern of the fracture, the amount of segmental bone loss, the occurrence of infection, and the use of external fixation. There were six delayed unions. Four patients had an angular malunion of more than 10 degrees, which spontaneously corrected in three. One patient who had a proximal metaphyseal-diaphyseal segmental fracture had a progressive valgus deformity. Four patients who had a severe fracture that was treated with external fixation had more than one centimeter of tibial over-growth. There were no amputations. The incidences of compartment syndrome, vascular injury, infection, and delayed union were similar to those reported for open tibial fractures in adults.

Anterior Compartment Syndrome↗
PubMed1989

Abnormalities of proximal femoral growth after severe Perthes' disease.

We studied the pattern of proximal femoral growth after severe Perthes' disease (Catterall grade III or IV) by retrospective analysis of serial radiographs in 52 hips (46 patients). Our aim was to determine the relationship between proximal femoral growth abnormalities and metaphyseal cysts, epiphyseal extrusion, physeal narrowing, and extensive epiphyseal necrosis. The average follow-up after treatment was 9.8 years (range 4 to 16 years), and 37 of the hips were followed to skeletal maturity. Slowing of proximal femoral growth was common: symmetrical abnormality was seen in 26 hips and asymmetrical abnormality in nine. However, definite premature closure of the proximal femoral physis was seen in only three hips. Abnormality seemed to be due to altered growth velocity rather than to bar formation in most cases. Metaphyseal cysts, epiphyseal extrusion and physeal narrowing during the active stage of the disease, alone or in combination, were found to be neither sensitive nor specific predictors of the subsequent growth pattern.

Adolescent↗
PubMed1988

Subtrochanteric osteotomy with intramedullary fixation for arthroplasty of the dysplastic hip. A case report.

Hip dysplasia in its end stage may require arthroplasty, and often extreme femoral anteversion is present. To correct rotational alignment of knee and hip joints yet preserve part of the femoral neck during total hip arthroplasty, a subtrochanteric derotational osteotomy was performed in a 37-year-old woman. Intramedullary fixation of the osteotomy was secured using a custom-fitted femoral component alone.

Adult↗
PubMed1988

2D and 3D computed tomography of the pediatric hip.

The contribution of computed tomography with multiplanar reconstructions (2D CT) and animated three-dimensional reformatting (3D CT) has been well documented in the adult hip. The applications and utility in the pediatric hip prove to be similar. Coronal and sagittal 2D images are superior to transaxial CT in defining the superior pole of the femur, the superior joint space, and the acetabular roof and dome. 3D CT provides the best overview of morphology, integrating the 2D information for therapeutic planning. Studies can be modified or tailored for dose control, particularly in the youngest patients.

Adolescent↗
PubMed1988

Comparison of femoral and innominate osteotomies for the treatment of Legg-Calvé-Perthes disease.

The outcomes of forty-two femoral osteotomies and forty-nine innominate osteotomies for the treatment of Catterall grade-III or IV Legg-Calvé-Perthes disease were compared. The average length of follow-up was nine years (range, three to seventeen years). For the patients who were less than ten years old at the onset of the disease, there was no difference in the results of the two procedures, even when the results were analyzed according to age. However, the center-edge angle, neck-shaft angle, lengths of the limbs, range of abduction, and total range of motion were closer to normal after an innominate osteotomy. There was no difference in the ratings when the results of the two operations were compared according to the several parameters that have been proved to be associated with the long-term outcome for hips in patients who have Legg-Calvé-Perthes disease. However, the innominate osteotomy seemed to be the better procedure when involvement of the growth plate was likely to cause coxa vara or a substantial discrepancy in the lengths of the limbs. The patients who were more than ten years old at the onset of the disease had a poor result with either procedure.

Casts, Surgical↗
PubMed1987

Results of surgical treatment of adults with idiopathic scoliosis.

The outcome of surgical treatment of idiopathic scoliosis in forty-five adults was studied with special attention to pain, function, self-image, and pulmonary function. All of the patients were more than twenty-five years old at operation and had been followed for more than three years. Every patient who was operated on by one of us (J. E. H.) and who met these criteria was evaluated. The magnitude of the curves averaged 66 degrees. Standardized gradations of pain and function showed improvement over-all, but significant impairment remained. There was a reduction in the levels of peak and constant pain, but no change in the frequency of peak pain after operation. The number of patients who were pain-free after surgery was not increased. Functional impairment due to the scoliosis was lessened, and the ability to perform the common activities of daily living was improved, but no important changes in occupation or recreational activity were recorded. Correlations of pain or function, or both, and the changes in either, were found with only two parameters: age at follow-up and physical occupation. Pulmonary function, as measured, did not change. Eighteen (40 per cent) of the patients had a minor complication and ten (20 per cent), a major complication; there was one death, due to pulmonary embolism, of a patient who was excluded from the series. In view of the high rate of complications, the limited gains to be derived from spinal fusion should be assessed and clearly explained to patients before the procedure is undertaken.

Activities of Daily Living↗
PubMed1984

Hip arthrodesis in young patients. A long-term follow-up study.

We evaluated the results in fifty-three patients who had had a successful hip arthrodesis at least twenty years (average, thirty-eight years) prior to the study and who had been less than thirty-five years old at the time of operation. We determined the functional history of each patient and the current status of the opposite hip, the knees, and the back. Radiographs were made and each joint was rated according to standard clinical scales. Seventy-eight per cent of the patients were satisfied with the arthrodesis, and all were able to work. Fifty-seven per cent had some low-back pain and 45 per cent, some knee discomfort. Only seven patients (13 per cent) had had a total hip arthroplasty on the arthrodesed hip.

Activities of Daily Living↗
PubMed1983

Double-entrapment radial tunnel syndrome.

A symptomatic double-level entrapment of the posterior interosseous branch of the radial nerve is described. In addition to the more common level of compression at its entrance into the supinator, the posterior interosseous nerve may be entrapped at its exit from the supinator or at multiple levels.

Anti-Inflammatory Agents↗
PubMedDate not supplied

Severe (type III) open fractures of the tibia in children.

Twenty children with acute type III open fractures of the tibial metaphyses or diaphysis were retrospectively studied. The average age was 9 years, 1 month (range, 2 years, 11 months to 16 years, 2 months). There were seven type IIIA fractures, 10 type IIIB fractures, and 3 type IIIC fractures. All fractures were irrigated and debrided, and prophylactic antibiotics were given for a minimum of 48 h. Fifteen fractures were initially treated with external fixation, three with casts, one with internal fixation, and one with a combination of external fixation and limited internal fixation. Free muscle flaps were used for soft-tissue coverage in six patients, and a local muscle flap in one patient. The average time to fracture healing was 29 weeks, and the median time to fracture healing was 20 weeks (range, 8-104). Four patients had delayed union, and two additional patients had nonunion. Both patients with nonunion were successfully treated with autologous bone grafting. The time to fracture union was related to the severity of soft-tissue injury, fracture configuration, segmental bone loss, and infection. Osteomyelitis developed in three patients. All were successfully treated. Two patients treated with external fixation had leg-length discrepancies of > 1 cm, with the injured extremity longer in both cases. There were no late amputations. Children with severe open fractures of the tibia have a good prognosis for limb salvage with aggressive wound care and fracture management.

Adolescent↗
PubMedDate not supplied

Dural ectasia in the Marfan syndrome: MR and CT findings and criteria.

PURPOSE: To create criteria for detecting dural ectasia on MR or CT images in adult Marfan patients. METHODS: Images were analyzed using a workstation. Parameters that predicted dural ectasia were included in our criteria. RESULTS: Major criteria include: (1) width of dural sac below L5 > width above L4; (2) anterior sacral meningocele. Minor criteria include: (1) L5 nerve root sleeve diameter > 6.5 mm and (2) S1 scalloping > 3.5. Dural ectasia exists if 1 major or 2 minor criteria are present. CONCLUSION: MR and CT diagnose dural ectasia with high specificity and sensitivity. Our criteria accurately diagnose dural ectasia in adult Marfan patients.

Adult↗
PubMedDate not supplied

A comparison of the Berlin and Ghent nosologies and the influence of dural ectasia in the diagnosis of Marfan syndrome.

PURPOSE: To compare the Berlin and Ghent diagnostic criteria for Marfan syndrome and evaluate the utility of screening for dural ectasia in the diagnosis of Marfan syndrome. METHODS: Review of clinical and radiographic data on 73 patients evaluated for Marfan syndrome at the National Institutes of Health. RESULTS: Nineteen percent of patients diagnosed under the Berlin criteria failed to meet the Ghent standard. Dural ectasia was the second most common major diagnostic manifestation, and screening for dural ectasia established the diagnosis of Marfan syndrome in 23% of patients under the Ghent criteria. CONCLUSIONS: Some patients are appropriately excluded from the diagnosis of Marfan syndrome by the Ghent criteria. Determination of dural ectasia is valuable in the diagnosis of Marfan syndrome.

Diagnosis, Differential↗
PubMedDate not supplied

Interspinous process segmental spinal instrumentation for scoliosis in cerebral palsy.

Interspinous process segmental instrumentation (ISSI) was used in 34 patients with scoliosis due to severe cerebral palsy. Average age was 17 years, and average curve was 82 degrees. Anterior fusion was performed in 21 patients before ISSI. Mean correction was 50.5%, and progression averaged 5 degrees at the 22-month follow-up. Posterior fusion alone gave good results in smaller curves. A brace was needed only for severe movement disorders. Gross functional level improved in fewer than one-third of patients. Minor gains were made by 74%. ISSI is effective in severe cerebral palsy. It may be used alone in the smaller (less than 80 degrees), more supple curves.

Adolescent↗
PubMedDate not supplied

Iliac crest growth plate analysis in slipped capital femoral epiphysis.

Previous studies have demonstrated numerous histologic and histochemical abnormalities in the involved growth plate of patients with slipped capital femoral epiphysis (SCFE). Whether these changes are primary or secondary with regard to the slip is unknown. We examined an uninvolved site of patients with SCFE and controls, the iliac crest growth plate, by histochemical means for general morphology, proteoglycans, glycoproteins, and collagen fibril orientation. No differences were noted between the two groups studied. This observation suggests that previously reported slipped capital femoral epiphyseal abnormalities may be a result of, rather than a cause of, the slip in this condition.

Adolescent↗
PubMedDate not supplied

Pediatric atlantoaxial instability presenting as cerebral and cerebellar infarcts.

Atlantoaxial instability can lead to severe, permanent neurologic compromise and death if not treated by cervical fusion. However, identification of atlantoaxial subluxation can be difficult owing to the often confusing signs and symptoms. We describe a patient with unexplained transient repeated cerebral and cerebellar signs who had 10 mm of translation of the atlas on the axis owing to os odontoideum with infarcts in the cerebellum and occipital parietal lobes. These correlated with angiographically documented vertebral artery narrowing at the level of the axis and the subsequent low flow to the posterior cerebellum. After stabilization and fusion of the cervical spine, the patient regained normal neurologic function and has remained symptom-free at 2 years of follow-up.

Atlanto-Axial Joint↗