PubMed Health⌕ Search

Biomedical subjects

P D'Aprile

Publications and source records attributed to P D'Aprile.

15 recordsLinked to original sources
PubMed2006

The value of fat saturation sequences and contrast medium administration in MRI of degenerative disease of the posterior/perispinal elements of the lumbosacral spine.

Degenerative-inflammatory lumbar spinal pathology is one of the most common reasons why individuals seek medical care, and low back pain is the main symptom among those most commonly associated with this pathologic condition. Pain is commonly attributed to degenerative disc disease, particularly herniated discs, but many different spinal and perispinal structures may undergo degenerative-inflammatory phenomena and produce pain: discs, bone, facet joints, ligaments and muscles. In particular, in patients with non-radicular low back pain, this syndrome may arise from changes of the posterior elements/perispinal tissues of the lumbar spine (i.e., the "posterior vertebral compartment"). They include: facet joint pathology (e.g., osteoarthritis, joint effusion, synovitis and synovial cysts), spondylolysis, spinal/perispinal ligamentous degenerative-inflammatory changes and perispinal muscular changes. It is well known that magnetic resonance is the most sensitive imaging method for the evaluation of spinal degenerative pathology, even in the initial stages of the disease. T2-weighted sequences with fat saturation, and when indicated the use of contrast-enhanced T1-weighted images with fat saturation, permit the visualization of degenerative-inflammatory changes of the posterior elements of the lumbar spine that in most cases would have been overlooked with conventional non-fat suppressed imaging.

Adipose Tissue↗
PubMed2000

Wernicke's encephalopathy induced by total parenteral nutrition in patient with acute leukaemia: unusual involvement of caudate nuclei and cerebral cortex on MRI.

We report a 13-year-old girl with leukaemia and Wernicke's encephalopathy induced by total parenteral nutrition. MRI showed unusual bilateral lesions of the caudate nuclei and cerebral cortex, as well as typical lesions surrounding the third ventricle and aqueduct. After intravenous thiamine, the patient improved, and the abnormalities on MRI disappeared.

Acute Disease↗
PubMed1994

Cerebral ischemia: magnetic resonance angiography and transcranial Doppler evaluation.

We examined 21 patients with ischemic cerebrovascular disease using magnetic resonance angiography and transcranial Doppler. In 17 patients (81%), the results obtained by the two methods were concordant. In our opinion, the associated use of transcranial Doppler and magnetic resonance angiography provides an accurate diagnostic evaluation of ischemic stroke patients, not only allowing the site of possible steno-occlusive disease of large and medium cerebral vessels to be identified, but also offering the possibility of obtaining dynamic information concerning the direction of blood flow in the presence of compensatory circulations at the level of Willis' circle.

Adult↗
PubMed1994

Enhanced MR in the acute phase of Wernicke encephalopathy.

MR in a patient with Wernicke encephalopathy showed enhancement in the mamillary bodies and inferior quadrigeminal plate. These findings pointed to the correct diagnosis, which can be difficult to make in patients who are not alcoholics.

Acute-Phase Reaction↗
PubMed1993

Magnetic resonance angiography monitoring of streptokinase in occlusion of the middle cerebral artery.

A 77 year old woman was hospitalized one hour after the onset of right hemiplegia and aphasia. Magnetic resonance imaging (MRI) examination was negative and MRA indicated occlusion of the left middle cerebral artery. Treatment with streptokinase was instituted (a 60 minute intravenous infusion of 1.5 MU of streptokinase in 100 ml of saline solution). Two hours after infusion, the patient's motor function clearly improved. An MRA examination performed six hours later showed partial recanalization of the obstructed vessel. Our report demonstrates the potential usefulness of MRA monitoring during thrombolytic therapy.

Aged↗
PubMed1990

Contrast materials with low iodine concentration and intra-arterial digital subtraction angiography.

Intra-arterial digital subtraction angiography was performed in 25 patients, using Iopamidol in three different iodine concentrations: 50, 75, and 100 mg I/ml and comparing the results obtained with each concentration. The following vessels were explored: the aortic arch, the common carotid artery, the internal and external carotid arteries and the vertebral artery. The contrastographic effect was satisfactory when lower iodine concentrations were used in very selective catheterizations while greater concentrations of iodine were needed in less selective procedures.

Adolescent↗
PubMed1989

MRI and CT evaluation of brain in neurofibromatosis. Case report.

Few MRI studies have been performed on subjects with Von Recklinghausen's neurofibromatosis. This not very well-known disease present lesions which in many cases do not appear on CT scans but may be detected by MRI. The nature of such lesions is still controversial. This paper will describe the case of a 7 year-old girl with neurofibromatosis. MRI examination revealed altered signals in some areas: in the basal nuclei, in the brainstem and in the white matter of the cerebellar hemispheres.

Brain Neoplasms↗
PubMed1984

Multiple meningiomas diagnosed by computed tomography.

This paper reports 11 cases of multiple meningioma diagnosed by CT in the three-year period 1980 to 1983. The pathogenetic problems raised by one case in which von Recklinghausen disease was associated are discussed.

Adult↗
PubMed1983

Brain-stem hemangioma calcificans. Case report.

A case of brain-stem hemangioma calcificans is described. The few cases reported in the literature prove the rarity of this tumor, which is considered a benign variant of cerebral cavernous hemangioma. Diagnosis and treatment of these tumors are briefly discussed with a review of the literature including 11 previous cases.

Adult↗