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Biomedical subjects

P Del Rio

Publications and source records attributed to P Del Rio.

At least 19 recordsLinked to original sources

Standardized laparoscopic right hemicolectomy technique for colon cancer.

AIM: We analysed our experience of laparoscopic surgical treatment vs traditional surgery of right colon cancer. METHODS: A series of 27 patients was treated from January 2001 to December 2005 out of a total of 927 surgical colorectal operations in the same period (147 with the laparoscopic approach). Inclusion and exclusion criteria are reported. We compared this group with 25 patients treated by the same surgical group with open surgery. The mean operative time, the distance from the distal margin of resection, the number of lymphnodes, the mean period of canalization and the mean hospital stay are reported. RESULTS: In the laparoscopic group, the mean operative time was 124.8+/-36.3 min vs open surgery group of 94+/-23.6 min; the distance from the distal margin was 6.7+/-3.1 cm vs 6.4+/-2.1 cm; number of lymphnodes was 15.2+/-4.3 vs 18.7+/-2.9 nodes; and canalization 1.7+/-0.9 vs 2.7+/-0.7 days. The hospital stay was 6.8+/-1.7 vs 7.2+/-0.8 days. CONCLUSIONS: We consider laparoscopic right colon resection a safe procedure but it needs good laparoscopic practice and the observance of inclusion criteria.

Adenocarcinoma↗

Complications of percutaneous endoscopic gastrostomy: a surgical experience.

AIM: Percutaneous endoscopic gastrostomy (PEG) is a practical and safe option to place an alimentary gastrostomy. We observed that a relevant rate of complications are related to management of PEG. PATIENTS AND METHODS: We registered the patients treated in our Unit from September 1994 to December 2005. We placed 293 PEG (243 pts). Preferably using a tube 16 Fr, in 7 cases 18 Fr, in 21 cases 20 Fr and only in 3 cases 9 Fr. The median age was 69.8 years; ratio female:male 3:1. In 67 cases the treatment was carried out in not hospitalized patients. RESULTS: The incidence of late and early complications is statistically higher in hospitalized patients than at home. CONCLUSION: We think that a correct management of PEG (nurses correct information) and the experience of endoscopist and a dietician can significantly reduce the rate of complications.

Aged↗

The size of pancreatic pseudocyst does not influence the outcome of invasive treatments.

BACKGROUND: Authors generally agree that Giant Pancreatic Pseudocysts (> 10 cm) have a lower spontaneous resolution and are more difficult to treat than smaller pancreatic pseudocysts. This study was carried out on two groups of patients with larger and smaller pancreatic pseudocysts (pancreatic pseudocysts > 10 cm versus pancreatic pseudocysts < 10 cm), and aims to establish whether the size of pancreatic pseudocysts is a factor influencing treatment outcomes. PATIENTS AND METHODS: In a retrospective study, we examined 71 patients with pancreatic pseudocysts following an episode of acute pancreatitis, which were treated in our hospital from 1980 to 2000. Forty-one (57.5%) patients had a large pancreatic pseudocyst. Most patients underwent invasive treatments: 9 (12.6%) had percutaneous drainage, 37 (52.1%) open surgery and 13 (18.3%) endoscopic cyst gastrostomy. 12 patients (16.9%) of the 71 were cured with medical therapy alone. RESULTS: As far as the aetiology of the pancreatitis, location and number of the cysts were concerned, no major differences emerged between the two groups, although large pancreatic pseudocysts followed more severe pancreatitis (P = 0.0005). All giant pancreatic pseudocysts required invasive treatments; 40% of the pancreatic pseudocysts < 10 cm were successfully treated with medical therapy alone. No statistical differences were found regarding hospital mortality, morbidity, recurrence rate and hospital stay among the patients treated invasively. CONCLUSIONS: Giant pancreatic pseudocysts more often require invasive therapy due to persistent symptoms or complications. Treatment outcomes do not seem to be influenced by the size of the pancreatic pseudocysts.

Adult↗

[Laparoscopic colectomy in the treatment of colon cancer: prospective study].

The Authors report their experience on laparoscopic colectomy in 38 patients treated between June 2001-September 2003 in General Surgery and Organ Transplantation Department of University of Parma, Italy. The patients were 23 male and 15 female, with average age 58.4 years. All patients were studied with TC and colonoscopy performed by the surgeon. The conversion rate was 15.8% and the average hospital stay 6.9 days (range 6-15 days). The patient's general clinical conditions and the results showed that the laparoscopic colectomy is a safe surgical option.

Colectomy↗

[Colorectal endometriosis].

The Authors present their experience from 1980 to 2001 in the treatment of 5 cases of endometriosis. The median age is 26.5 years, the symptomatology was the presence of abdominal pain feces mixed with blood in two patients and in three cases a colorectal localization as well as a pelvic endometriosis. In a case the Authors have treated the patient with a surgical approach and in the others with a medical therapy with LH-RH analogs. Pathogenesis, symptomatology, diagnostics, medical and surgical therapy of this disease are also analyzed.

Adult↗

[Early complications of thyroid surgery].

The complications in thyroid surgery reported in literature are variables. The Authors describe the experience on 803 thyroidectomy from 1 January 1995 to 31 December 2000. The knowledge of the embryologic origin of the parathyroids glands, of the causes of haemorrhage and the improvement of the surgical technique has permitted a lower incidence of complications.

Adult↗

[Breast carcinoma in accessory gland: a case report].

The Authors we report the case of a 50 year old woman with accessory breast cancer in the thoracic region. The examination revealed a mass of 1 cm diameter and a tumorectomy showed a ectopic breast with an intraductal carcinoma. Nodal dissection, chemo-, radio- and hormonal therapy there performed. The follow up didn't show a relapse of breast carcinoma after 5 years.

Antineoplastic Agents, Hormonal↗

Breast cancer in pregnancy.

Breast cancer in pregnancy involves a psychosocial, religious, multidisciplinary medical decision. From 1991 the Authors have surgically treated six patients affected by breast cancer in pregnancy. The Authors, in this papers, review analysing current therapeutic approach for this disease.

Adult↗

[Medullary carcinoma of the thyroid gland].

We report the experience of the Institute of Surgical Pathology of the University of Parma on three patients with sporadic medullary thyroid carcinoma (MTC). MTC is a tumor of parafollicolor cells origin (C cells). The surgical excision of the thyroid tumor and cervical node metastases is potentially curative. The other therapeutic options are limited. Considerable emphasis has been placed on early diagnosis and surgery for multiple endocrine neoplasia (MEN) related MTC. Genetic screening promises earlier and accurate diagnosis (RET gene mutations are found in MEN).

Adult↗

[Diagnosis and surgical treatment of primary hyperparathyroidism].

Primary hyperparathyroidism (HPP) is increasingly being recognized because of the widespread use of multiphasic screening for hypercalcemia, in patients without clinical signs. Each year develop 100,000 new cases in the United States, females/males 5:2; the peak of incidence is in V-VI degrees decade. We analyze our patients from November 1975 to July 2000. We have performed 112 parathyroidectomy for HPP, 84 females and 28 males, median age 57.5 years. We have examined the surgical options, the value of PTH, calcium, and the number of pathological glands. The Authors discuss the invasive or non-invasive procedures and the surgical treatment.

Adolescent↗

[Biopsy of sentinel lymph nodes in the treatment of breast carcinoma: experience of the Surgery Department of the Hospital of Parma].

Radical axillary nodes dissection in breast cancer is a standard for a correct staging, unfortunately this approach can cause several unpleasant sequelae and complications. Sentinel node biopsy applied to breast tumors could be a good option for predicting axillary nodes status avoiding complete dissection. The aim of this work is to report our experience with sentinel node biopsy during a period of 18 months. One hundred and nine patients with an infiltrating breast tumor T1 had been studied. There wasn't clinical and ultrasonographic evidence of axillary infiltration. Tumors had been injected on the day before surgery with a mixture of colloidal human albumin particles marked with 99m Technetium. In 108 out of 109 patients (99%) sentinel node had been identified using a gamma probe and biopsied during surgical intervention performed under local anesthesia. Sentinel node has been examined both with conventional histology and immunohistochemistry. In 26 cases the node was positive for metastases. Radical axillary dissection in this subgroup of patients showed that in 85% of them sentinel node was the only positive. We conclude that sentinel node biopsy can be a good alternative to traditional axillary dissection but there are still important questions about the best method of analysis and, before the technique become a routine procedure in breast cancer management, we should know the results of prospective clinical trials comparing survival of patients staged by sentinel node biopsy versus traditional axillary dissection.

Adult↗

[Gastric polyps: possible causes of pyloro-duodenal obstruction].

We reported three cases of transpyloric prolapsed polipoid lesions. Abdominal pain, early satiety are the most common presenting features. Endoscopies and polipectomy are important for a correct diagnostic evaluation. Large polyps (> 2 cm), if prolapsed, can require a surgical excision.

Aged↗

[Merkel-cell carcinoma. A report of 3 clinical cases].

The finding of Merkel cell carcinoma is a rare but important event owing to the highly aggressive nature of this neoplasm. The authors report three cases of Merkel cell carcinoma with different onsets which were representative of the possible range of clinical symptoms and the prognosis of this pathology. In two cases diagnosis was made by chance, but in the third case a preoperative biopsy was initially performed with subsequent radicalization. The authors examine the diagnostic and therapeutic protocols proposed by other authors and compare them to their personal experience to ensure early diagnosis and radical therapy. Surgery is the obligatory initial choice, followed by radiotherapy and an accurate follow-up. The authors evaluate the use of Octeotride therapy for tumours of neuroendocrine origin and hence its application to Merkel cell carcinoma.

Aged↗

Pre-operative evaluation and treatment of patients with chronic venous insufficiency.

OBJECTIVE: To describe the use of radionuclide venography (RV) in the detection of the site(s) of blood reflux through incompetent perforating veins (IPVs) of the leg of patients with chronic venous insufficiency (CVI). EXPERIMENTAL DESIGN: Prospective study in which we evaluated our experience in the assessment and treatment of patients with moderate or severe CVI with a follow-up ranging between 6 and 48 months. SETTING: A surgical service of the Department of Surgery of the University of Rome "Tor Vergata". PATIENTS: Fifty-three patients with CVI that were referred to our service to be surgically treated. INTERVENTIONS: Physical examination, RV, and surgical procedures of ligation of IPVs. MEASURES: Based on pre- and post-operative physical examination and RV. RESULTS: The patency of deep venous system and the presence of 1 to 3 leg IPVs was confirmed preoperatively in all the limbs either with physical examination and RV. After surgery, non-ulcerated skin changes improved and all the ulcers healed within 45 days. Postoperative RV showed that the IPVs had disappeared from the affected areas in 56 limbs. Two ulcers recurred after two and six months respectively. CONCLUSIONS: RV showed to be a reliable method to exactly detect IPVs. This method is useful to guide the ligation of IPVs in patients with moderate or severe CVI.

Aged↗

[One-lobe Caroli's disease (report of a clinical case].

A patient affected by Caroli's disease without congenital fibrosis, 80 y. old is reported. The Caroli's disease was asymptomatic all life long; this was a intraoperative finding and only in the last year the patient presented recurrent cholangitis. The "simple" Caroli's disease is less common than other forms. We analyze the literature and the ethiopathogenetic mechanisms hypotisized.

Aged↗