PubMed HealthSearch

Biomedical subjects

P Delouche

Publications and source records attributed to P Delouche.

5 recordsLinked to original sources

Influence of pulsatility on the development of intracardiac jets: an in vitro laser Doppler study.

So far, it has been hypothesized that numerical data obtained in steady flow conditions apply to pulsatile flows. In order to study the modifications of the velocity fields due to pulsatility, jets were produced by 8 orifices (with a diameter "D" of 4.4 to 11.3 mm) included in a chamber of 50 mm. The velocity was measured using laser Doppler anemometry with a pulsatile flow ("pf") and compared to the values obtained in steady ("sf"): at maximum velocity, the longitudinal velocity profile is qualitatively similar to this observed in steady flow: it is made of a plateau followed by an hyperbolic velocity decay in the turbulent area. The length of the core ("Lpf") is strongly related to "D" (Lpf = 3.72 D + 5.49, r = .99) and the velocity decay depends on the ratio between the distance "x" from the orifice and "D" (V/Vo = 2.83D/x + 3.46, r = .85, where V is the velocity at "x" and Vo the initial velocity). During the acceleration and the deceleration, the laminar core is disturbed by turbulences. The comparison of "pf" data with "sf" data demonstrated similar diameters at the origin of the jets (Dpf = 0.96 Dsf + .12, r = .99), but significant (p less than .0001) differences both for "L" and "V/Vo": Lpf = .91Lsf + 6.58, r = .97, V/Vopf = .63 V/Vosf + .34, r = .76. Thus, pulsatility modifies velocity fields and the results obtained in steady flow conditions do not apply to pulsatile jets.

Animals

In vitro analysis of a model of intracardiac jet: analysis of the central core of axisymmetric jets.

In order to provide physical information supporting the clinical use of flow mapping, an in vitro model was designed to measure the velocity fields in a pulsatile hydraulic turbulent jet. We used a peak velocity ranging from 2.5 to 5.5 m.s-1, an orifice diameter ranging from 5.8 to 11.3 mm and confined the jet in a receiving tube whose diameter ranged from 16 to 30 mm, thus simulating a large variety of valvular leaks. In steady flow conditions, our results agreed with previously reported descriptions. Under pulsatile conditions, the same structure was found at peak velocity and during the beginning of the deceleration. Below a threshold velocity, the length of the central core was independent of the peak velocity and proportional to about six times the orifice diameter. Above the threshold velocity, this relationship was no longer true, the threshold value being related to the ratio of the orifice diameter to the diameter of the receiving tube.

Blood Flow Velocity

Limitations of ultrasound imaging and image restoration.

The definition of medical ultrasound images is strongly limited by the need for low examination frequencies which is imposed by the high attenuation of acoustic waves in tissues. The filtering effect of imaging systems is described and quantified for echography, transmission tomography and reflection tomography. Improvement of image definition is demonstrated to be the result of a numerical restoration of the received echoes implemented, in the present case, by a simplified Kalman filter. The improvement in definition obtained is emphasized on simulated data and tissue images. The comparison between the results obtained from the three techniques shows that: if only echography provides a real-time acquisition of signals, tomographic methods lead to faster processing associated with a better signal-to-noise ratio on the reconstructed images, and reflection tomography offers the best definition.

Animals