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Biomedical subjects

P Derevenco

Publications and source records attributed to P Derevenco.

At least 19 recordsLinked to original sources
PubMed1986

Central and peripheral effects of 6-hydroxydopamine on exercise performance in rats.

6-Hydroxydopamine (6-OHDA) injected into the lateral cerebral ventricles of rats impaired their exercise performance until exhaustion (treadmill run and swimming). The injected rats displayed significantly less training-induced improvement of swimming performance than did the control animals. Reduced performance also was seen in adult rats treated intraperitoneally with 6-OHDA in the neonatal or adult periods. The functional impairment can be explained by the neurotoxic action of 6-OHDA on monoamine brain structures (substantia nigra and locus ceruleus) and/or on peripheral sympathetic innervation, the latter assessed by histofluorescence of the iris muscle. The possible contribution of lacticacidemia to the reduced tolerance to stress of 6-OHDA-treated rats by the intracerebroventricular route also is considered.

Adaptation, Physiological↗
PubMed1975

Action of some pituitary hormones on the work capacity in rats.

FSH (50 mu/rat X 12 days), ICSH (in the same dosis) and gonadotropinum sericum (20 U/rat X 13 days) have a prevailing inhibitory influence on the motor activity in untrained or/and trained rats. TSH raises the motor performance but significantly only in great doses (1.5 IU/100g body weight X 13 days). GH (0.1 and 0.5 mg/rat X 16 days) reduces the favourable effects of moderate training on the run performance. A part of these results could be explained by the studied biochemical changes.

Animals↗
PubMedDate not supplied

Undersea psychophysiologic reactions of human organism.

The determinations carried out on 12 divers during the immersion into the sea to a depth between 7 and 29 m, as well as on controls in immersions at 4 m revealed a significant prolongation of the visual reaction time and a marked tachycardia. The changes were more marked at great depths and if exercise was superimposed over hyperbaric stress. A rise in the urinary excretion of 17-HOCS and vanillylmandelic acid and an impairment of the manual dexterity were also found during immersions. The results stress the importance of divers' monitoring during their underwater activity and the necessity of improving their physical training.

17-Hydroxycorticosteroids↗