Metastasis from choriocarcinoma of the mediastinum producing acute appendicitis.
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Acute Disease↗
Biomedical subjects
P Dhimes
Publications and source records attributed to P Dhimes.
Primary malignant lymphoma of the uterine cervix: report of a case with cytologic and immunohistochemical diagnosis.
A non-Hodgkin's lymphoma initially diagnosed on the cervical smear in a 69-year-old asymptomatic female is described. The cytologic findings strongly suggested the presence of a malignant lymphoid neoplasm: neoplastic cells were round, loosely arranged, with scanty cytoplasm and cleaved nuclei. Histological evaluation of the cervical biopsy revealed a diffuse lymphoid proliferation of mononucleated cleaved cells beneath an ulcerated epithelium. Immunohistochemically, the tumour cells were positive for B cell markers. Reports on cytologic features of primary malignant lymphoma of the cervix are not frequent in the literature. We emphasize the importance of their recognition and the differential diagnosis of cervical lymphoma from other neoplastic and non-neoplastic lesions.
Aged↗
Gastrointestinal autonomic nerve tumours and their separation from other gastrointestinal stromal tumours: an ultrastructural and immunohistochemical study of seven cases.
Gastrointestinal stromal tumours (GIST) represent a heterogeneous group whose classification frequently requires ultrastructural and immunohistochemical studies. In a retrospective study of the ultrastructural findings of 24 gastrointestinal stromal tumours, whose light microscopic study has yielded ambiguous results and in which accurate diagnosis had required ultrastructural support, seven were found to have the characteristics of gastrointestinal autonomic nerve (GAN) tumours. In all of them the diagnosis was based on the presence of dendritic processes with dense neuroendocrine granules. Immunohistochemically, the seven tumours were negative for smooth-muscle markers. All stained positively for vimentin. NSE, chromogranin, and synaptophysin were positive in most of them, while S-100 protein was positive only in two cases. We present the ultrastructural and immunohistochemical features of seven GANT against the background of the GISTs of our series. We conclude that GAN tumours cannot be diagnosed by light microscopy alone but this tumour group displays characteristic electron microscopic and immunohistochemical features and appears to represent a distinct type of GIST.
Adult↗
Prolapsed hyperplastic gastric polyp causing pancreatitis: case report.
A huge hyperplastic gastric polyp prolapsed into the duodenum. The compression and obstruction of the ampulla of Vater by this polyp caused acute pancreatitis. An overview of imaging findings, general considerations about hyperplastic gastric polyps, and a review of the literature are provided.
Acute Disease↗
Microinvasive follicular thyroid carcinoma detected by fine needle aspiration skeletal metastases. A case report.
BACKGROUND: Fine needle aspiration biopsy (FNAB) for the cytologic diagnosis of bone metastatic lesions is often useful for locating the primary tumor and choosing treatment. The cytologic picture of follicular carcinoma most commonly resembles normal thyroid but may exhibit variable anaplasia. Marginal vacuoles, also known as fire flare-like vacuoles and "flame cells," have been found mainly in toxic goiter but also in some non-toxic goiter. The presence of marginal vacuoles of FNAB of metastatic follicular carcinoma was first reported by Pitts et al in 1988. CASE: A 77-year-old male presented with multiple lytic lesions involving the vertebral bones and ribbons. FNAB of vertebral bone showed tumor cell clusters in a follicular pattern with peripherically situated, pink-stained vacuoles on May-Grünwald-Giemsa stain. CONCLUSION: FNAB is useful in the diagnosis of metastatic thyroid neoplasms. The recognition of marginal vacuoles, along with the appropriate cytologic findings, should provide morphologic clues leading to a suspicion of thyroid neoplasm metastasis in FNAB.
Adenocarcinoma, Follicular↗
Subareolar abscess of the breast in a male. A report of two cases with fine needle aspiration cytology diagnosis.
BACKGROUND: Fine needle aspiration (FNA) is a well-established method for the diagnosis of breast diseases in males, but very little attention has been focused on inflammatory lesions. Previous reports do not mention subareolar abscess (SA), which is a distinct entity in breasts of females. CASES: Two adult males presented for FNA of recurrent breast masses located near the nipple. Smears from both patients showed the typical cytologic features of SA. CONCLUSION: Recognition of this troublesome and rare condition on FNA cytology from the breasts in males will prevent recurrences since SA is not cured by excisional biopsy.
Abscess↗
Nodular cervical induration in a violinist. Report of a case with fine needle aspiration cytologic findings.
BACKGROUND: Nodular indurations due to repeat trauma have been previously described. These subcutaneous lesions have been reported as occupational disease in male cyclists ("accessory testicles"). CASE: The cytologic findings from a case of nodular cervical induration in a 47-year-old violinist are reported. It consisted of a well-delimited, nodular lesion in the left submandibular soft parts. Fine needle aspiration cytology (FNAC) smears showed few spindle cells with no atypia and scarce adipocytes in a collagen background. CONCLUSION: FNAC findings are important in the differential diagnosis of cervical nodules. In this case, the subcutaneous nodule was a violinist's occupational disease, for which we propose the term "violinist's nodule."
Biopsy, Needle↗
Ultrastructural study of a perineurioma with ribosome-lamella complexes.
The participation of the perineurial cell in peripheral nerve tumors is the subject of much debate. The case of a 75-year-old female with a soft tissue tumor on her left shoulder is presented. The tumor had histological, ultrastructural, and immunohistochemical characteristics of a pure perineurial cell neoplasm. Ultrastructurally, distinctive ribosome-lamella complexes were found in the cytoplasm of the perineurial cells. This may be the first time that these structures have been described in perineurioma.
Aged↗
The alcohol-drop solution: an aid in cytologic screening.
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Alcohols↗