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Biomedical subjects

P Drobec

Publications and source records attributed to P Drobec.

13 recordsLinked to original sources
PubMed1983

The value of the edrophonium tonography in the diagnosis of myasthenia gravis.

Tonography of the eye was performed after administration of 10 mg edrophonium chloride (Tensilon) in 13 patients with clinically diagnosed myasthenia gravis. In ten of these patients repetitive nerve stimulation was used to examine the function of the motor end-plate. A significant pressure rise (more than 2 mm Hg) within the 1st min after edrophonium administration was observed in three patients (four eyes), whereas eight of the ten patients who underwent nerve stimulation showed positive results. The edrophonium tonogram test does not seem to be significant enough to define the diagnosis in early myasthenia gravis. Beyond this, these tests might have lost some of their value due to the introduction of antibody analysis against acetylcholine receptors, which serve as a very sensitive diagnostic tool now.

Adolescent↗
PubMed1983

[Hemorrhagic secondary glaucoma after central venous thrombosis].

Patients suffering from neovascular glaucoma who had been treated at the First Vienna University Eye Clinic in the years 1966-1979 were analyzed recently in a retrospective study. The present paper concentrates on 144 cases of hemorrhagic secondary glaucoma after central venous thrombosis. It considers only those patients who had not undergone laser therapy prior to vascular occlusion. The items dealt with in detail are the clinical symptoms, the early and rapid loss of vision, the high intraocular pressure, the interval between the occurrence of the vascular occlusion and the neovascular glaucoma, the distribution among age groups and sexes and the relation to general diseases.

Adult↗
PubMed1983

[Incidence and significance of fundus changes in EPH gestosis].

The authors examined 100 unselected pregnant women with EPH gestosis of different severity using the Keith-Wagener classification. In 52 women no fundus changes were observed; first-degree changes were seen in 32 women and second-degree changes in 10. Six gravidae presented with third or fourth-degree fundus changes. The average gestosis index was almost identical in the group without fundus changes and in the groups with first and second-degree hypertensive retinal changes, but significantly higher in the group with severe fundus changes (third or fourth degree). There was a clear correlation between the hypertensive fundus changes and blood pressure at the time of examination, in particular with regard to systolic blood pressure. An apparently normal fundus did not exclude the presence of a severe EPH gestosis; on the other hand severe retinal changes were sometimes seen in women with only mild EPH gestosis. Examination of the fundus in patients with EPH gestosis permits an objective assessment of vascular changes and provides a basis for further obstetric management.

Adult↗
PubMed1982

[Immunological investigation in primary open angle glaucoma (author's transl)].

It is a matter of discussion in literature, if autoimmunological processes are involved in the pathogenesis of primary open angle glaucoma. Therefore we determined circulating Clq binding immune complexes, collagen antibodies, antinuclear antibodies and anit-nDNA-antibodies in the sera of patients with this disease. The result of our investigation and of recent papers lead to the conclusion that autoimmunological processes- are not involved in the pathogenesis of primary open angel glaucoma.

Adult↗
PubMed1982

[Hemorrhagic glaucoma (author's transl)].

Drawing in 15 840 patients treated at the First Eye Clinic of the University of Vienna between 1966 and 1980, 273 cases of hemorrhagic secondary glaucoma were selected for a special study. After a historical review of the semantic change which the expression "hemorrhagic glaucoma" has undergone etiological factors are investigated. Hemorrhagic glaucoma occurred after occlusion of the central retinal vein in 52.7% of the cases, as a result of diabetes mellitus in 37.3%, after iridocyclitis chronica recidivans in 3.7%, following retinal detachment in 1.8%, as a result of intraocular tumors in 1.8%, after occlusion of the central artery in 1.1% and after an apoplectic shock in 0.4%.

Diabetes Complications↗
PubMed1981

[Comparison of betamethasone and clobetasone butyrate eye drops and their effect on intraocular pressure (author's transl)].

The effect of clobetasone butyrate eye drops on ocular pressure was tested in 15 steroid responders suffering from different types of conjunctivitis and compared with betamethasone eye drops. Elevated intraocular pressure following application of 0.1% betamethasone eye drops decreased significantly within 2 weeks under medication with 0.1% clobetasone butyrate 4 times daily, whereas fellow eyes kept under treatment with betamethasone suffered further increases in IOP. The therapeutic effect and subjective compatibility of the two steroids were found to be approximately equal.

Betamethasone↗
PubMed1981

[Corneal sensitivity in chronic open-angle glaucoma (author's transl)].

Corneal sensitivity was measured in 91 eyes suffering from chronic open-angle glaucoma using the electronic-optical hand esthesiometer after Draeger. It was found that the threshold value in eyes with glaucomatous cupping or atrophy of the optic nerve was significantly increased, in contrast to eyes with normal optic disks, but that there was no direct relationship between IOP at the time of measurement and the duration of the open-angle glaucoma. The reduced sensitivity was due to damage of the long ciliary nerves between the choroid and sclera. The authors' findings thus support the view that glaucomatous atrophy of the optic nerve is caused by primary pressure atrophy of the retina.

Adult↗
PubMed1980

[Subvitreal hemorrhage in a case of juvenile hypertension with aneurysm of the internal carotid artery (author's transl)].

The etiology of subvitreal hemorrhage in the course of subarachnoidal hemorrhage is briefly considered. The coincidence of juvenile hypertony and subarachnoidal hemorrhage resulting from intracranial aneurysms is then discussed. The necessity of timely vitrectomy is pointed out, with reference to a case of the author's in which intravitreal hemorrhage showed no tendency to resorption during a follow-up period of six weeks, and in which after a pars plana vitrectomy an organizing preretinal hemorrhage was eliminated.

Adult↗
PubMed1980

[The influence of blood coagulation on cicatrization of the filtering scar following goniotrepanation (author's transl)].

An examination of 43 eyes which had undergone goniotrepanation in accordance with Fronimopoulos showed that blood coagulation plays a major part in the postoperative cicatrization of the filtering scar. Patients with short postoperative haemorrhages or with high rates of thrombocytes tend to suffer postoperative hypertension of the eye, whereas patients with haemorrhages of over 1 minute or with low rates of thrombocytes often have the clinical symptoms of postoperative hypotony.

Adult↗
PubMed1978

[Treatment of herpes simplex keratitis with Vidarabin ointment (author's transl)].

In 20 cases of herpes simplex keratitis the efficacy of Vidarabin ointment has been tested, in 19 cases after corneal abrasion. The eyes were treated once a day and padded until the epithelial defects had closed. Thereafter the ointment was applied 4 times per day for about one week more. On the average epithelial closure had been achieved after 2.4 days, complete normalization of the epithelium after a total of 3.6 days. This therapy results in a considerable shortening of the healing process as compared to the topical use of anti-viral medication alone. From this aspect Vidarabin ointment has proved to be a valuable adjuvant.

Clinical Trials as Topic↗
PubMed1977

[Senile lattice structures in the parenchym of the cornea (author's transl)].

Sharply limited, intersecting, optically void, dark appearing lines in the parenchym of the cornea of elder patients may be called senile lattice work. They are presumably caused by general decay, they are benign and do not impair the visual faculty. A knowledge of them is of significance for differential diagnosis.

Age Factors↗