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Biomedical subjects

P E Calonius

Publications and source records attributed to P E Calonius.

At least 19 recordsLinked to original sources

Desmoplastic fibroma involving the mandible.

Desmoplastic fibroma is a rare, benign, fibroblastic tumour arising intra-osseously. A case in a 13 year-old male is described. A tumour, situated between the roots of the right mandibular canine and premolar, was excised in 1984. Morphologically, the characteristics of the tumour conformed well to those of a desmoplastic fibroma. The differential diagnosis of desmoplastic fibroma with reference to the histopathological and ultrastructural appearance of the tumour is discussed.

Adolescent↗

Peripheral squamous odontogenic tumour.

Squamous odontogenic tumour (SOT) is a rare, benign epithelial tumour of odontogenic origin. A recurrent case of SOT with peripheral occurrence is described. In 1971, a tumour from the anterior maxillary palatal mucosa of an 11-year-old female was excised. In 1984, when the patient was 24 years old, a recurrent tumour was found in the same area. The histopathological appearance of the lesion, which was found to be identical with the primary tumour, was that of an SOT. Both the clinical and radiographic features supported the extra-osseous involvement of both tumours. The SOT is further evaluated and its origin is discussed.

Child↗

Primary intra-osseous carcinoma involving the maxilla.

Primary intra-osseous carcinoma, especially in the maxilla, is a rare sub-type of odontogenic carcinoma. The authors describe a recurrent case with maxillary involvement. In 1981, an intra-osseous maxillary tumour was excised from a 33 year-old male. There were two recurrences (in 1983 and 1984). Extra-osseous sites for the origin of the tumour were excluded. The histopathological appearance of the tumour was that of a primary intra-osseous carcinoma. At the age of 22 years, the patient had an osteosarcoma of the radius and at the age of 31 years, pulmonary tuberculosis. The differential diagnosis of primary intra-osseous carcinoma is discussed.

Adult↗

Central neurilemmomas of the mandible. Report of a case.

Central neurilemmomas involving the jaws are rare benign tumours probably originating from the neural sheath. We report 2 cases involving the posterior part of the mandible. The 1st case (male, age 20 years) had no symptoms of a tumour, which was discovered by accident in an orthopantomogram. The 2nd case (female, age 66 years) had experienced pain because of a tumour. The radiographic appearance of these tumours seemed to be non-specific. These 2 neurilemmomas have recurred, probably due to incomplete primary removal of the tumour.

Adult↗

Transplantation of free tibial periosteal graft on alveolar bone defect in adult rabbit.

The healing of bone defect in eight adult rabbits was studied. The age range of animals was 5-23 months. The bone defects were made symmetrically in the inferior surface of the mandibles. At the defect site the root surface of continuously erupting mandibular incisors was exposed. On the left side, the bone defect was covered with a local periosteal flap (control side) and on the right side the defect was covered with a free periosteal graft from the tibia (test side). The healing of bone defects and the amount of new bone were studied. The quality of the bone formed was investigated histologically. The findings of this investigation led to the following conclusions: (1) The bone defects healed on both sides. The amount of bone on the control side was identical to that in the anatomical region. On the test side the amount of bone formed was in seven cases two to threefold that formed on the control side. (2) The histological study proved that the bone formed was lamellar bone, being identical on both the control and the test side. (3) The ages of the animals or the length of follow-up time did not affect the amount of new bone, the healing of the defect or the quality of new bone. (4) The eruption of the incisors was symmetrical. In this study the free periosteal graft from the tibia led to better bone formation than the local periosteal flap in the induced bone defects of the tooth-bearing region in the mandible of the adult rabbit.

Age Factors↗

44-year dental health survey of Helsinki schoolchildren.

The purpose of the present study was to establish whether the number of intact teeth in Helsinki schoolchildren aged 7-13 years was rationally correlated with the wartime reduction in sugar consumption and, later, with dental health education programs in Finland. The period covered is 44 years. The results show that dental health education is effective in caries prevention and that enforced programs can lead to an improvement similar to that seen during the war.

Adolescent↗

Calcifying epithelial odontogenic tumor (Pindborg tumor) case report.

A 36-year-old woman was examined and treated for a rare odontogenic tumor in the mandible, the calcifying epithelial odontogenic tumor (CEOT), also known as the Pindborg tumor. The tumor extended from the left mandibular molar region to the right premolar area and had almost completely destroyed the bone in the anterior mandibular region. An orthopantomogram showed a multiloculated radiolucent lesion, with an unerupted tooth in the center surrounded by a radiopaque area. In addition, finely granular calcification was visible here and there in the tumor area. In the histologic examination the tumor tissue could be identified as calcifying epithelial odontogenic tumor. Under electron microscopy the fibrillar structure at the basal cell level suggested the presence of amyloid. The tumor was removed by enucleation with a collar of surrounding tissue. No signs of recurrence have been noted at follow-up examinations.

Adult↗

Teeth loss and the inflammation of teeth-supporting tissues in rheumatoid disease.

To compare the state of dentition between rheumatoid and control patients, ortopanthomograms were taken of 126 rheumatoid and 119 control patients. This roenthenologic examination revealed a signficantly higher incidence of teeth loss among the rheumatoid patients than among the control patients. To determine whether the dental periapical lesions of patients with rheumatoid disease differ histologically from corresponding lesions in control patients, the dental periapical lesions of 43 rheumatoid and 23 control patients were examined with a routine histochemical technique. No differences were detected however between these two patient groups either as regards the histologic features of their periapical lesions or as regards the incidence of these lesions, whether granulomas or radicular cysts. Furthermore, examination of the gingival tissues from 21 rheumatoid patients did not either reveal any distinguishing histologic feature. Amyloid was sought in the teeth-supporting tissues of both rheumatoid and control groups with techniques involving light, polarization and fluorescence microscopy. In neither group was amyloid detected with certainty with any of these techniques. The higher incidence of teeth loss among rheumatoid patients invited further investigation into the relationship between dental health and rheumatoid disease.

Adolescent↗