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Biomedical subjects

P E Kim

Publications and source records attributed to P E Kim.

5 recordsLinked to original sources

The trigeminal nerve.

The trigeminal nerve is the largest of the cranial nerves, serving as a major conduit for sensory information from the head and neck and primarily providing motor innervation to the muscles of mastication. An understanding of the pathologic processes that may involve this nerve requires a detailed knowledge of its origin within the brain stem as well as its course intracranially. This article describes the neuroanatomy of the nerve and divides it into its various segments to provide a differential diagnosis of common and some uncommon pathologic processes.

Brain Stem↗

Imaging of neurocysticercosis.

Neurocysticercosis produces a variety of neurologic syndromes resulting from the cysticerci infestation of the central nervous system by the larvae of Taenia solium. Because of increased immigration to the United States from endemic areas, the incidence of neurocysticercosis has increased, especially in California, Texas, Arizona, and other southwestern states. Neuroimaging studies play a significant role in the diagnosis and management of patients with neurocysticercosis.

Brain↗

Fungal infections of the central nervous system.

The diagnosis and treatment of central nervous system fungal infections typically pose problems for the clinician. With an increased incidence of fungal infections in immunocompromised patients, neuroradiologic imaging has become essential in determining complications and outcomes. This article provides a summary of the more common organisms encountered in fungal infections of the central nervous system and the imaging features primarily seen with CT and MR imaging.

Brain↗

Association of invasive pneumococcal disease with season, atmospheric conditions, air pollution, and the isolation of respiratory viruses.

We examined the relation of invasive pneumococcal disease to season, atmospheric conditions, and the rate of respiratory virus isolation in a community-wide surveillance program in Houston. Among adults, the number of cases of pneumococcal bacteremia peaked in midwinter and declined strikingly in midsummer, indicating a high degree of inverse correlation with the ambient temperature. We detected significant correlations between the occurrence of pneumococcal disease and the isolation of respiratory syncytial virus (P < .001), influenza virus (P < .001), and all viruses except influenza virus (P < .001), as well as with air pollution, as measured by SO2 levels (P < .001). In contrast, the rate of invasive pneumococcal disease among infants and children was relatively more sustained from October through May, with a notable decrease in summer months; the incidence of pneumococcal disease was therefore less strongly correlated with cold weather and less closely associated with the isolation of respiratory syncitial virus or influenza virus. However, pneumococcal disease among infants and children was associated with isolation of these viruses after a 4-week lag period as well as with isolation of adenovirus and ragweed pollen counts. The finding, with regard to children, that correlations tended to be stronger for events that occurred 1 month previously than for those that occurred contemporaneously is consistent with the concept that viral or allergic events predispose to otitis media with effusion, which becomes suppurative and leads to pneumococcal bacteremia or meningitis. For adults, a more immediate predisposition to pneumococcal pneumonia and bacteremia because of viral infection or air pollution was suggested.

Adenoviruses, Human↗

The radiologic evaluation of craniocerebral missile injuries.

A brief overview of the imaging findings in craniocerebral missile injury is presented here. CT scanning has established itself as the primary imaging modality for the complex injuries seen in CMI as well as its acute and delayed complications. Plain x-ray, angiography, and magnetic resonance imaging have more limited but sometimes important roles in the management of these injuries. With regard to outcome prediction, imaging has also proved to be of some, albeit limited, usefulness, primarily as adjuncts to clinical criteria such as the GCS. Future research with CT as well as magnetic resonance imaging will likely expand the clinical role of these modalities, particularly in the realm of outcome analysis.

Brain Injuries↗