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Biomedical subjects

P Eckart

Publications and source records attributed to P Eckart.

3 recordsLinked to original sources

[Reflux nephropathy].

Reflux nephropathy is characterized by the presence at radiological examination of one or several segmental scars in the renal parenchyma, associated with vesico-ureteral reflux. Histology displays a variety of lesions, among which chronic and atrophic pyelonephritis, segmental hypoplasia and renal dysplasia can be individualized. Most of these renal lesions can be prevented by early detection of the reflux which encourages the development and recurrence of urinary tract infection and its diffusion to the upper urinary tract and the kidneys. The finding of a vesico-ureteral reflux with renal lesions, even after spontaneous or surgical regression of this reflux, requires prolonged surveillance in view of the long-term risk of arterial hypertension and renal failure.

Child

Multicentric Kaposi's sarcoma in a 5-year-old human immunodeficiency virus-negative renal allograft recipient.

We describe the clinical and pathologic features of a case of pediatric multicentric Kaposi's sarcoma (KS) associated with allograft transplantation in a human immunodeficiency virus (HIV)-negative child. A lethal polyadenopathic and visceral KS occurred in a 5-year-old Caribbean boy who had undergone an allogenic renal transplantation for diffuse mesangial sclerosis with end-stage renal failure 4 months previously. The HIV-1 and HIV-2 serologies were negative. Despite its rarity, KS must be considered as a differential diagnosis in posttransplantation polyadenopathic or multisystemic syndromes in children.

Autopsy

[Moebius syndrome with pharyngo-laryngeal paralysis in a premature infant].

A case of Moebius syndrome in a premature baby is reported. After a phase of neonatal severe respiratory distress syndrome, the baby presented with a persistent facial paralysis, already present at birth and inability to close the eyes (also present in her father), without ophthalmoplegia. An unusual pharyngeal and laryngeal paralysis was also present: it led to tracheal intubation then tracheostomy and gastrostomy. CT scan at 15 months of age showed hypoplasia of brain stem. The difficulties of managing bulbar paralysis in such a premature baby are emphasized.

Facial Paralysis