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Biomedical subjects

P Efrati

Publications and source records attributed to P Efrati.

At least 19 recordsLinked to original sources
PubMed1979

Myeloproliferative disorders terminating in acute micromegakaryoblastic leukaemia.

Two cases of myeloproliferative disorder--one of myelofibrosis with agnogenic myeloid metaplasia and one of chronic granulocytic leukaemia terminating in acute micromegakaryoblastic leukaemia--are presented. The clinical course is described, and results are reported of morphological, cytometric, cytochemical and cytogenetic studies, as well as cell culture of blood cells in soft agar and in fluid medium.

Adolescent↗
PubMed1979

Pseudo-Chediak-Higashi anomaly in acute myeloid leukaemia. An electron microscopical study.

2 cases of acute myeloid leukaemia with inclusion bodies are presented. The inclusions were found mainly in the blast cells but could also be encountered in lymphocytes and plasma cells. Cytochemical and ultrastructural studies showed a great resemblance of these inclusions to the ones found in Chediak-Higashi anomaly, i.e., high acid phosphatase activity, varying in size of inclusions from clusters of small granules to hugh inclusion, sometimes found in vacuoles, featuring fusion of lysosomes.

Acid Phosphatase↗
PubMed1977

Semiquantitative cytochemical estimation of beta-glucuronidase activity in peripheral lymphocytes in healthy human subjects.

A semiquantitative cytochemical evaluation of beta-glucuronidase activity in peripheral lymphocytes in 123 normal sybjects was made. It was found that the enzymatic activity was influenced by age but not by sex. Activity was weak in newborn infants but increased with age and reached maximal values in old subjects. Age should therefore be taken into consideration when the enzyme activity is evaluated.

Adolescent↗
PubMed1976

Effect of serum from leukapheresed mice on myelocytes, promyelocytes and colony-forming cells.

Leukapheresis of neutrophil granulocytes in mice increased the myelopoietic activity of their serum. Leukapheresed mouse serum (LMS) caused a threefold increase in the in vitro stathmokinetic index of myeloid precursors. Five to ten minutes of incubation were sufficient to change the colony-forming capacity of mouse bone marrow cells as expressed by the increase in the ratio of granuloid to erythroid cells in spleen colonies. The in vitro stathmokinetic index assay also showed that there are diurnal variations in levels of granulopoietic activity in normal mouse sera. However, at any time of the day, LMS had higher granulopoietic activity.

Animals↗
PubMed1976

Morphological and cytochemical investigation of human mesothelial cells from pleural and peritoneal effusions: a light and electron microscopy study.

We investigated the morphological and cytochemical properties of mesothelial cells obtained from pleural and peritoneal effusions of patients with various diseases. The morphological features were studied by light and electron microscopy and by cytochemical methods. The different kinds of contact between mesothelial cells and their interaction with lymphocytes were observed and the transition of mesothelial cells to macrophages and/or fibroblasts was demonstrated.

Ascitic Fluid↗
PubMed1969

[The monocyte].

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Journal Article↗