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Biomedical subjects

P Enzler

Publications and source records attributed to P Enzler.

6 recordsLinked to original sources
PubMed1988

Ectopic ossification following total hip arthroplasty: is diffuse idiopathic skeletal hyperostosis a risk factor?

Total hip arthroplasty may be followed by ectopic bone formation. An increased frequency has been suspected in patients with diffuse idiopathic skeletal hyperostosis (DISH). In 204 patients we found that, of the 38 subjects with pre-existing DISH, 29% developed postoperative ossification compared with only 10% in those without DISH (p less than 0.01). DISH is therefore a risk factor for postoperative ectopic bone formation. In a separate study of 1325 patients (not analysed for spinal DISH), we looked for correlations between the severity of postoperative ectopic bone and clinical measurements. Even for the more severe ossification grades (n = 112), only 10% reported serious pain and only 26% had reduced hip flexion (less than 70 degrees). Thus, periprosthetic ectopic bone is not sufficiently important to justify the routine use of preventative drugs such as bisphosphonates in patients with DISH undergoing total hip replacement.

Adult↗
PubMed1985

[Lung varices. A case report].

Pulmonary varices are dilated pulmonary veins with normal anatomy of pulmonary venous return. Etiology, diagnostic procedures nd different forms of pulmonary varices are discussed. Surgery is indicated for thromboembolic or hemorrhagic complications, or, as in the case of our patient, for suspected malignoma.

Adult↗
PubMed1984

[The Mirizzi syndrome].

Three cases of Mirizzi's syndrome are reported, with special emphasis on differential diagnosis and preoperative evaluation. The syndrome consists of the triad cystic duct stone, inflammatory reaction and benign hepatic duct stenosis. Endoscopic retrograde cholangiography or percutaneous transhepatic cholangiography is mandatory for preoperative evaluation. Cholecystectomy with clearance of the bile duct is the treatment of choice.

Cholecystectomy↗
PubMed1980

[Antibodies against native deoxyribonucleic acid (anti-nDNA) without antinuclear antibodies: clinical significance (author's transl)].

Antinuclear antibodies (ANA) by indirect immunofluorescence and antibodies against native deoxyribonucleic acid (anti-nDNA) by radiommunoassay were measured simultaneously in 6,000 sera from about 5,000 patients. Usual findings about 5,000 patients. Usual findings were: (a) both tests negative (75%), (b) only ANA positive (20%), and (c) both tests positive (3%). The unusual combination of ANA-negative/anti-nDNA positive was found in 117 sera from 24 patients. These patients were examined more closely clinically and the mentioned tests repeated. In five with systemic lupus erythematosus, in two with chronic rheumatoid arthritis and one with chronic urticaria this finding occurred repeatedly over some time. In five additional patients (two with chronic hepatitis, one each with drug-induced systemic lupus erythematosus, chronic rheumatoid arthritis, and drug related haemolytic anaemia) this unusual finding occurred only once but with high levels of anti-nDNA. In 11 patients with various diseases the combination of ANA-negative/anti-nDNA positive occurred only once, with the anti-nDNA value being low. In a control group of patients with mononucleosis, cytomegalic disease, acute or chronic hepatitis or hepatoma, anti-nDNA results were never positive.

Anemia, Hemolytic↗