[Testicular pseudotumor and constitutional syndrome].
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Biomedical subjects
Publications and source records attributed to P Ergueta Martín.
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OBJECTIVES: To analyse the entered more frequent disease in an Internal Medicine Department, the reasons for hospital admission diagnosis at discharge (according to entrance symptom's guide), the group of affected population and its correlation among them. PATIENTS AND METHODS: Over a total of 758 internal medicine admissions of the University Hospital of Valladolid during the year 1999 based on the information of discharge and clinical histories, a descriptive and observational epidemic study was made using the variables of sex, age, reason for admission (guide symptom) and diagnosis at discharge. The obtained results were represented by mean of diagrams of sectors and bars according to the analyzed variables. The data synthesis was made by measures of central tendency and dispersion. SPSS 10.0 version for windows program was used for the statistical study. The non parametric analysis for independent samples was made by the test of median and the U of Mann Whitney, and the parametric by chi-squired test and resistance of Kolmogorov-Smirnov. RESULTS: The median of age is 70 years. Rank 84 years. Interquartile rank 23, fashion in men 75 years and in women 86. The distribution in sex men 51%, women 49%. The more frequent reasons for entrance are dyspnea (35%) and neurological focus (11%). The more frequent diagnosis at discharge are dyspnea and chronic obstructive lung disease worsened by respiratory infection (11%), pneumonia (8%) and acute ischemic stroke (7%). CONCLUSIONS: In-patients in this service, are advanced in years (mainly women) (alpha = 0.05). The age does not get a normal distribution (alpha = 0.05). The frequency of the distribution in sex is similar. The most frequent reason for admission is dyspnea (35%). The most frequent diagnoses at discharge are chronic obstructive lung disease (11%), pneumonia (8%) and acute ischemic stroke (7%). The primary and secondary prevention and an improvement of the therapeutic measures of chronic cardiopulmonary disease would reduce significantly the welfare pressure in Internal Medicine Department and they would improve the population's life quality given that we are opposed to the diseases which are among the four first mortality causes in the world.
OBJECTIVE: To determinate the influence of the acarbosa and microalbuminuria on metabolic parameters in patients diabetics type 2. RESEARCH DESIGN AND METHODS: We are studied 92 patients with diabetes type 2, treated with Acarbose alone or with insuline or oral anti-diabetics We are determined the values of HbA1c, total cholesterol, HDL, LDL, triglycerides and microalbuminuria, before and after or the treatment with acarbose. RESULTS: The patients presented globally a statistically significant improvement in the levels of Hb A1 c, triglycerides and microalbuminuria. In the group treatise with 300 mg/day of acarbose it was observed a significant decrease of the values of Hb A1c and triglycerides independently of the associated treatment. In the group treated with 150 mg/day the improvement only it was statistically significant for the levels of Hb A1c. CONCLUSIONS: The treatment with acarbose produces an improvement in the levels of Hb A1c independently of the administered dose and of the triglycerides in patients treated with 300 mg/day without relation to associated treatments. Therefore, he acarbose win be considered an effective medication to improve the metabolic control to prevent the cardiovascular risk in those patients.
OBJECTIVE: To determinate if fibronectin in CSF can be a useful parameter in the diagnosis of some neurologic illnesses. MATERIAL AND METHODS: We have studied 30 patients, subdivided in four groups, depending on the type of neurologic illness. We have chosen as control a 10-patient group, which came to the Emergency Service and were diagnosed as a suspicious of neurologic illness, but after this it was discarded. In the whole group we practiced a lumbar puncture, with cytology, systematic, biochemistry, cultures, immunoglobulins determination and fibronectin quantification by ELISA. RESULTS: We want to emphasize the increase in fibronectin levels in CSF in both the patients with bacterial meningitis and the multiple sclerosis groups, when it's compared with the control group. CONCLUSION: For this, the determination of fibronectin levels in CSF might be a useful parameter in the diagnosis of some neurologic illnesses.
OBJECTIVES: Superior vena cava syndrome (SVCS) is an uncommon disease which receives usually bad prognostic. In order to study the prevalence of the different etiologies we have reviewed retrospectively 17 documented cases of SVCS in the last 5 years. METHODS: The range of age was between 43 and 80 years Sex distribution was 16 males and 1 female. RESULTS: Malignant pathology was by large the most common etiology. Oat cell and squamous cell carcinoma account each for 20%, adenocarcinoma for 18%, undifferenciated carcinoma for 12% and Hodgkin's disease for 6%. Among the benign causes we have found a case of retroesternal goiter.
The relevance of the diabetological education in the treatment of diabetis mellitus must be a prioritary goal in order to reach a proper metabolic control and to avoid as much as possible both acute metabolic complications and long-term vascular and neurological complications, achieving thus a total integration of the diabetic patient in the society. We have monitored during 15 days a group of diabetic children with IDDM in a summer camp, assessing in all of them several clinical and biochemical parameters. The results have been statistically analyzed using the Student's test. After the stay in the summer camp, we observed a significant reduction in the total dose of insulin (p < 0.001) and in the number of hypoglycemias (p < 0.001) and an increase in the average levels of capillary glycemia at the end of the study period when compared with the beginning, with p < 0.001 (breakfast preprandial), p < 0.05 (lunch preprandial) and p < 0.01 (dinner and night preprandial). We did not observe any significant differences in the other parameters studied. In inclusion, the stay in the summer camp of this group had a positive effect, achieving a better metabolic control with lower doses of insulin.
A clinical case of a man with calcification of basal ganglions (CBG) is presented. The first manifestations of this syndrome were loss of consciousness and convulsions. The potential causes of his hypocalcemia, Fahr's syndrome, myocardiopathy of hypoparathyroidism and hypocalcemia are reviewed and a study oriented to autoimmune polyendocrinopathy is performed.
Blood pressure variations of 30 insulin-dependent diabetic patients free of complications, and aged between 14-35 years have been studies, comparing their results to those from a control group formed by healthy person of the same age and physical features. Median systolic pressure of diabetic population was 120 +/- 11.07, compared to 112.90 +/- 11.31 from control group. The median diastolic pressure of diabetic population was 76.76 +/- 10.12 and 67.40 +/- 7.94 of the control group. A significant difference on systolic (p less than 0.05) and diastolic (p less than 0.001) pressures were observed in insulin-dependent diabetic patient comparing their results to those from the control group.
A new case of DIDMOAD syndrome is reported on. A complete description is given and the sequential associations are detailed; highlighting the fact that the frequently associated urinary alterations should be considered as part of the same disease.
We study 48 compensated diabetic patients, 41.6% of whom were male, 68.75% had diabetic neuropathy and/or vascular complications (macro-microangiopathy). In 60.4% of the patients the study began at ten years of disease evolution. We selected 14 healthy adults as a control group, 50% being male. Plasma levels of T3, T4 and TSH were measured by RIA and the antimicrosomal antibody (AMT) and antithyroglobulin antibody (ATG), detected by passive hemagglutination. A significant decrease in T3 level (p less than 0.05) was found in controlled diabetic patients, compared to T3 levels of the control group; there was a significant reduction in T3 level (p less than 0.05) in diabetic patients with vascular disease and in female diabetics (p less than 0.05), compared to the control group. There were no statistically significant differences in the other groups, including other parameters measured. We concluded that there is a decrease of T3 in all diabetic patients, this being more noticeable in diabetic females and diabetic patients with vascular disease.
Pericarditis and cardiac tamponade are very rare complications of inflammatory disease of the bowel. A case of a patient with ulcerative colitis, who subsequently developed pericarditis, cardiac tamponade and pleural effusion during a latent phase of the baseline disease, is presented. At the same time, the papers published on this subject are reviewed. The presence of dyspnea, tachypnea, of pleuritic pain in patients with ulcerative colitis must be taken into consideration, and all the tests necessary to study a pleuropericardial pathology should be performed.
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