[Modifications of gas exchange during moderate muscular exercise in transitory regimen].
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Biomedical subjects
Publications and source records attributed to P Escourrou.
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OBJECTIVE: Our aim was to evaluate the consequences of polyhydramnios on maternal plasma volume and maternal serum aldosterone and atrial natriuretic peptide (ANP) concentrations in monochorionic twin pregnancies complicated by twin-to-twin transfusion syndrome (TTTS). METHODS: The maternal plasma volume, ionograms as well as plasma ANP and aldosterone concentrations were compared in normal monochorionic diamniotic twin pregnancies and in TTTS. RESULTS: The maternal plasma volume was normal in TTTS despite severe polyhydramnios. The plasma aldosterone concentration was higher in pregnancies complicated by TTTS. CONCLUSION: The high plasma aldosterone concentration is likely to maintain normal plasma volume despite progressive extravascular volume enhancement. This suggests that TTTS is present early in pregnancy as a chronic phenomenon starting before its clinical expression and may trigger compensatory maternal hyperaldosteronism.
An experimental study of three different types of oxygenator was carried out in the dog during two hours extra corporeal circulation. The hemodynamic aspects and the characteristics of pulmonary elasticity that a previous study permitted us to choose as controls of the quality of extracorporeal perfusion, were studied. The results show that the pulmonary arterial resistances and the indices of pulmonary compliance do not recover during E.C.C. to their initial values, in the case of an E.C.C. using a bubble oxygenator. These results should be taken into consideration in the choice of the most suitable oxygenator.