PubMed HealthSearch

Biomedical subjects

P Etches

Publications and source records attributed to P Etches.

3 recordsLinked to original sources

Selective elevation of circulating prostaglandin concentrations in hyaline membrane disease in pre-term infants.

The plasma concentrations of prostaglandins E and F (PGE, PGF) and 13, 14-dihydro-15-keto-PGF (PGFM) have been measured in pre-term neonates with hyaline membrane disease (HMD) and controls. The concentrations of PGF and PGFM were significantly higher in infants having HMD with a disproportionate increase in PGFM levels for the increase in PGF found. The vasoconstrictor nature of PGF may contribute to the morbidity associated with HMD and the possible therapeutic benefit from the use of prostaglandin synthetase inhibitors is discussed.

Humans

Rhythmic habit patterns (stereotypies).

Rhythmic movements such as head-rolling, head-banging and body-rocking are seen in normal children in early life, but much more commonly in the mentally handicapped. Emotional disturbance and boredom tend to increase the movements. Various theories have been advanced to account for these stereotyped patterns. They appear to be intentional and may satisfy some inner need or allay frustations, but it is concluded that their true significance is unknown.

Affective Symptoms

Cystinotic rickets treated with vitamin D metabolites.

A 22-month-old girl with cystinotic rickets was given 1 microgram 1,25-dihydroxycholecalciferol (1,25-DHCC) daily in addition to standard treatment. Her rickets healed and linear growth rate appeared to increase. It is suggested that the effect of 1,25-DHCC and its metabolically active analogues on cystinotic rickets should be further studied.

Cystinosis