Biomedical subjects

P F Basso

Publications and source records attributed to P F Basso.

4 recordsLinked to original sources

PubMed1994

Association of neuromyotonia with peripheral neuropathy, myasthenia gravis and thymoma: a case report.

A case of neuromuscular hyperactivity syndrome associated with a thymoma, high serum titres of anti-acetylcholine receptor and anti-DNA antibodies is reported. The study of peripheral nerve conduction revealed a peripheral neuropathy. Repetitive stimulation showed a decrease in the fifth M response. Myasthenic symptoms were anamnestically reported but were absent at clinical observation. The clinical picture and EMG examination improved after phenytoin administration.

Autoantibodies↗

PubMed1990

Epilepsy in multiple sclerosis.

In a series of 2,353 multiple sclerosis (MS) patients, 40 subjects presented seizures, with an overall prevalence of 1.70%. The prevalence was 2.33% (34/1,459) in definite MS cases, 0.58 in probable cases (3/518), 0.79 in possible cases (3/376). Twenty-six patients were females, 14 were males. In 13 cases, epilepsy had begun before MS onset; in 4 patients, the two diseases started contemporarily; in 23 patients, epilepsy followed MS onset. No relationship was found between frequency of seizures and course of MS nor between frequency of seizures and MS severity. In 12 patients, magnetic resonance imaging was performed: plaques adjacent to the cerebral cortex were found in 3 cases. The electroencephalogram showed paroxysmal discharges in 11 patients (focal in 2, diffuse in 9). Slow theta and/or delta activity was found in 15 patients (focal in 7, diffuse in 6, both focal and diffuse in 2). The EEG was normal in 14 patients. Possible etiological factors other than MS were recognized in 4 patients only: cranial trauma in 3, meningitis in 1. Our study on a large MS population confirms that MS is associated to a risk for epilepsy higher than that of the general population.

Adolescent↗

PubMed1979

[Levodopa treatment of a case of torsion spasm with athetosis].

The result about Levodopa treatment in torsion dystonia and athetosis are quite contradictory. We report an interesting case, significant for the results that we obtained in a long treatment period. A girl was suffering from age of 8 years of torsion dystonia associated with athetosis. We made our first clinical examination when 12 years old: she was not able to stand-up and to walking, neither was she able to be sitting in a chair without arms. In two months of treatment with Levodopa 3.000 mg. by day, the symptoms completely disappeared. During the first two years of treatment, at every effort to decrease the therapy we observed an important increase of symptoms. Successively it was possible to decrease the therapy and now, after 8 years of treatment, with a minimal dose, the girl doesn't show any symptoms, so that she can manage a normal relative life. Probably these good results depend on the fact that was a sporadic recessive form of torsion dystonia case.

Athetosis↗

PubMedDate not supplied

[Aggressiveness in humans].

Aggressiveness is a deeply-rooted feature of human biology. Its underlying mechanisms can be analysed doctrinally from the biological standpoint, in the light of physiological, clinical and pharmacological data, the ecological standpoint, wherein comparison is made with the behaviour patterns observed in animals, and the psychological standpoint, which is strongly influenced by psychoanalysis theory in explaining the reasons for aggressive behaviour. Reference is also made to the form taken by aggressiveness in children, adults and persons with neurological and mental diseases. The ways in which pathological aggressiveness can be treated are discussed.

Aggression↗