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Biomedical subjects

P F Mason

Publications and source records attributed to P F Mason.

11 recordsLinked to original sources
PubMed1997

Post-thoracotomy chylothorax--a cure in the abdomen?

Operative control via a thoracic approach of chylothorax can be difficult to achieve, particularly if the chyle leak is secondary to previous thoracic surgery. This report describes the ligation of the thoracic duct at the level of the diaphragmatic hiatus, via an abdominal approach. This technique was the definitive management in four of the last 5 patients presenting with chylothorax in our unit. Typically the leak ceased within 24 h with early discharge of the patient from hospital.

Abdomen↗
PubMed1996

The management of chronic fissure in-ano with botulinum toxin.

Five patients with a chronic fissure in-ano each received an injection of Clostridium botulinum type A toxin into the lower internal anal sphincter. A mean lowering of maximum resting anal pressure by 23.3 (SEM 5.6) cm H2O was achieved within seven days. Maximum voluntary squeeze pressures were not significantly altered. Anal compliance increased in all cases. Healing of the fissure with an apparent reduction in anal sensation occurred in three of the patients and partial resolution of symptoms in the other two. No adverse effects resulted from injections of the toxin. A controlled trial to compare the relative efficacies of botulinum toxin and lateral sphincterotomy is required.

Adult↗
PubMed1994

The assessment of cerebral oxygenation during carotid endarterectomy utilising near infrared spectroscopy.

Near infrared spectroscopy is a non-invasive method for continuous monitoring of tissue oxygenation. In 11 patients undergoing unilateral carotid endarterectomy, changes in cerebral oxygenation following carotid cross-clamping and declamping detected by a near infrared spectrometer were compared with corresponding changes in ipsilateral middle cerebral artery flow velocity measured by transcranial Doppler ultrasonography. Spectroscopic traces were obtained in all patients but adequate Doppler signals in only eight. Changes in cerebral haemoglobin oxygenation correlated closely (r = 0.908, p < 0.001) with changes in middle cerebral artery velocity. The near infrared spectrometer was also sensitive to the changes in cerebral haemodynamics due to intraoperative hypo- and hypertensive episodes. No evidence of cerebral intracellular hypoxia was seen and all patients made an uneventful recovery. Near infrared spectroscopy compares well with transcranial Doppler ultrasound as a monitor of cerebral function during carotid endarterectomy and may have a future role in the elucidation of cerebral perfusion and oxygenation changes following surgery.

Aged↗
PubMed1992

Testicular epidermoid cyst--is pre-operative diagnosis possible?

A case of testicular epidermoid cyst which had initially been misdiagnosed as a malignant testicular tumour is presented. The role of clinical and ultrasound examination in the pre-operative assessment is discussed. Although the benign nature of this condition must be demonstrated histologically before conservative surgery is contemplated, it is equally important that the patient should not be told that the tumour is malignant without adequate evidence.

Adult↗
PubMed1991

Increasing infantile hypertrophic pyloric stenosis? Experience in an overseas military hospital.

Fifty-four children with proven infantile hypertrophic pyloric stenosis (IHPS) were treated by Ramstedt's pyloromyotomy during a 14-year period. Between the years 1986 and 1989 the mean incidence of the disease was noted to have risen by 2.72 per 1000 live births over the preceding 10 years. Statistical analysis confirmed a significant upward trend between the years 1976 and 1989. Analysis of the majority of the cases revealed comparable perioperative morbidity rates with other UK district general hospitals. There was no operative mortality. The character of IHPS in military personnel overseas has more in common with UK than international trends. The incidence in this subgroup may be rising.

Germany↗