TENSION GRADIENTS ACCOMPANYING ACCELERATED OXYGEN TRANSPORT IN A MEMBRANE.
Facilitated transport of oxygen through hemoglobin has been studied by use of a membrane sandwich of hemoglobin, Teflon, and water. Transport is enhanced only when there is a hemoglobin-bound-0(2) gradient in the pigment. When passing through a fully oxygenated layer, the accelerated transport is carried by an increased diffusion gradient of oxygen pressure through the solvent. The results substantiate experimentally the diffusion gradients proposed by Zilversmit.
Biochemical Phenomena↗