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Biomedical subjects

P F Scanlon

Publications and source records attributed to P F Scanlon.

15 recordsLinked to original sources

A comparison between intubation and food addition as routes of oral exposure for northern bobwhites to DDT insecticide.

Our objective was to compare two methods of oral dosing of p,p'-DDT (1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane) on uptake of DDT metabolites and isomers (i.e., p,p'-DDT, o,p'-DDT, p,p'-DDE, o,p'-DDE, p,p'-DDD, o,p'-DDD) in livers and brains. p,p'-DDT was administered to northern bobwhite (Colinus virginianus) by intubation with corn oil or as a feed additive for 56 days. When adjusted for amount of DDT consumed, total DDT (sigma DDT, the summation of all DDT metabolites and isomers) and p,p'-DDE concentrations differed significantly (P less than 0.10) in both brains and livers, whereas p,p'-DDD differed only in brains and p,p'-DDT differed only in livers. Paired comparisons between brains and livers differed significantly for sigma DDT, (P less than 0.05), p,p'-DDE (P less than 0.05) and p,p'-DDT (P less than 0.1) for both intubated and food-dosed treatment groups, whereas p,p'-DDD (P less than 0.05) differed only in the intubated group. We concluded that method of oral exposure affected the uptake of DDT in livers and brains for northern bobwhites.

Administration, Oral

Heavy metal levels in feathers of wild turkeys from Virginia.

Levels of lead, cadmium, nickel, and zinc were determined in feathers of 175 wild turkeys (Meleagris gallopava) shot by hunters in 19 Virginia counties in 2 physiographic regions. Lead and nickel levels did not vary by county, region, sex, or age. Zinc and cadmium levels were significantly (P less than 0.01) higher in adult turkeys.

Age Factors

A modified blow-gun syringe for remote injection of captive wildlife.

A modified syringe capable of automatic injection and suitable for use with a blow-gun is described. The syringe has been used successfully with white-tailed deer (Odocoileus virginianus) under confined conditions. Desirable characteristics for blow-gun syringes are discussed.

Animals

Lead levels in small mammals and selected invertebrates associated with highways of different traffic densities.

Lead levels in small mammals were studied in 6 areas -- 3 associated with highways of different traffic densities, and 3 control sites in forested areas. Lead levels were also studied in insects from 2 traffic areas and in earthworms from different distances from 2 traffic areas. Lead levels were low in insects ranging from 3.84 microng/g to 3.35 microng/g. Lead levels in earthworms were highest in those recovered closest to highways and from the area with the higher traffic volume. Lead levels in mammals generally was highest in mammals from areas of higher traffic densities. Higher levels of lead were found in shrews than in Peromyscus and Microtus.

Animals

Lead concentrations in soil and vegetation associated with highways of different traffic densities.

Soil lead levels were found to decrease significantly in all traffic areas as distance from the highway increased. Areas of higher traffic volume had greater soil lead levels. Strong trends were shown in vegetation with areas of greater traffic density having greater lead levels than areas of lower traffic density. A decrease in lead levels was also noted in vegetation as distance from highway increased.

Lead

Orientation of cattle fetuses in utero in relation to stage of pregnancy.

The orientation in utero of cattle fetuses was studied in 494 pregnant cows (478 singly pregnany; 16 twin pregnant). Fetuses were in anterior presentation if the head was oriented toward the cervix and in posterior presentation if the head was oriented toward the uterotubal junction. Data were considered for 10 day stages of gestation (Day 40 to 170) and for 15 day stages (Day 171 to 280). Before 100 days and between 101 and 200 days of pregnancy the proportion of fetuses in anterior presentation approximated 50%. After 201 days of pregnancy 82.7% of fetuses were in anterior presentation, and orientation was different (x-2 equals 16.49:1 df) from random (50:50). After 216 days all fetuses were in anterior presentation. Data from twin pregnancies were too few to be conclusive, but no trends were dissimilar from those in singly pregnant cows. Anterior presentation of fetuses is assumed not later than 216 days of gestation in normal pregnancies.

Animals

A male pseudohermaphrodite white-tailed deer resembling an antlered doe.

A male pseudohermaphrodite white-tailed deer (Odocoileus virginianus) is described. The animal shot in Aiken County, South Carolina on November 4, 1971, was 1.5 years old and had the external appearance of an antlered doe. The 6 point antlers were in velvet, a vulva was present, and the testes were located in the body cavity. Other male reproductive organs present were epididymides, vasa deferentia and ampullae. Female reproductive organs present were cervix, vagina and clitoris.

Animals

Histology and ultrastructure of kidney tissue from ringed turtle doves that ingested lead.

Ringed turtle doves (Streptopelia risoria) ingested 4 x 122 mg lead pellets or lead acetate (75 micrograms Pb/g body weight) and their kidneys were examined by histological and electron microscopic techniques. Doves that received lead treatments had readily discernable lead intranuclear inclusion bodies in cells of the proximal convoluted tubules. At 33,000 X, the inclusions had a characteristic dense central core, and outer fibrillary zone. Necrosis in the proximal tubular area was seen as deterioration of cell cytoplasm and reduction in mitochondria. In doves ingesting lead, histological evaluation of proximal convoluted tubular cells revealed acid-fast pinkish granules in cell nuclei. Inclusions from rapidly as 1 dove that died after receiving the first of two lead doses (75 micrograms Pb/g body weight/day) had relatively small intranuclear inclusions in cells of the proximal convoluted tubules.

Animals