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Biomedical subjects

P F Taylor

Publications and source records attributed to P F Taylor.

6 recordsLinked to original sources

The threatening stare: differential response latencies in mild and profoundly retarded adults.

Institutionalized retarded adults (N = 120) were studied using a 2 (mild, profound) x 2 (stare, no stare) x 2 (close, far) analysis of variance design. It was expected that threatening-stare conditions would produce smaller response latencies for avoidance and aggressive behavior than would the no-stare condition and, further, that the stare would have greater impact on the profoundly as compared with mildly retarded subjects, especially in the close conditions. These expectations were supported by the response latency data that yielded a highly significant main effect for stare and significant Stare x Retardation and Stare x Distance interactions.

Adult↗

Effects of growth inhibitors and ultraviolet irradiation on F pili.

The effects of chloramphenicol, nalidixic acid, mitomycin C, NaCN, and ultraviolet irradiation at 253.7 nm on F pili production by Escherichia coli cells was studied by electron microscopy. The results show that cells contain pools of pili protein, and that assembly does not require synthesis of protein or deoxyribonucleic acid (DNA). NaCN (2 x 10(-2)m) prevents the reappearance of pili and causes existing pili to disappear quickly from the cell surface. This suggests that energy is used in the assembly of pili and to retain pili on the cell. Cells irradiated with high doses (10(4)ergs/mm(2)) of 253. 7 nm light produce fewer pili, and these are shorter than normal. Dose-response curves for number of pili per cell and length of pili resemble single hit kinetics, showing 37% survival at 10(4) ergs/mm(2) and 2 x 10(4) ergs/mm(2), respectively. This suggests that DNA is at the site where pili are produced, and that it may be involved in the assembly of pili.

Bacterial Proteins↗

Bone-anchored craniofacial prosthesis study.

A prospective study involving 24 centers and 145 patients was conducted to evaluate the long-term osseointegration survival rate for titanium implants anchoring a craniofacial prosthesis (auricular, orbital, or nasal) and to evaluate the long-term retention and stability of the prosthesis. Of 452 implants placed, 19 were lost (overall survival rate of 96%). Of the 145 patients, 115 were evaluated (remained active) throughout the study period and were followed-up for at least 30 months. The results of the study suggest that the bone-anchored craniofacial prosthesis system is a viable alternative to conventional reconstructive surgery and offers significant improvement in the quality of life when compared with the support systems previously available for these types of prostheses.

Adolescent↗

Bone-anchored craniofacial prosthesis study: irradiated patients.

A prospective study involving 24 treatment centers and 145 patients was conducted to evaluate the long-term osseointegration success rate for titanium implants anchoring a craniofacial prosthesis (auricular, orbital, and nasal), and to evaluate the long-term retention and stability of the prosthesis. Twenty patients (14%) in this study had received prior irradiation therapy, and 60 implants were placed in these 20 irradiated patients. Nine of the 60 implants were lost (85% survival rate). Although the few patients and few implants may not allow for conclusions to be drawn, analysis and review of the data on these irradiated patients may assist in reliable and valid comparisons to be made with other published studies.

Adult↗