Biomedical subjects

P Ferron

Publications and source records attributed to P Ferron.

7 recordsLinked to original sources

PubMed1992

[Multivariate study of auditory perception using multi-electrode cochlear implants].

The goal of this study was to determine the influence of auditory and cognitive factors in hearing or listening mechanisms with the Nucleus multielectrode cochlear implant. Accordingly, hearing sensitivity, psycho-acoustical masking functions and measures of temporal resolution were obtained from 14 adults with acquired deafness. In addition, six measures of open-set speech discrimination were introduced to represent a possible contribution of cognitive factors. Results indicated the contribution of both auditory and cognitive factors to speech understanding. Cognitive factors were most influential. Differences were also found in the relative importance of various cognitive factors, both before and after an intensive aural rehabilitation program. Initially, subjects relied more heavily on their ability to make efficient use of the linguistic redundancy of speech. At the end of the program, they paid more attention to speech acoustics, as a result of enhanced auditory spectral analysis and temporal resolution at about 2 kHz.

Adolescent↗

PubMed1992

Detection of Helicobacter pylori-like organisms in the stomach of some food-source animals using a monoclonal antibody.

To investigate a possible animal reservoir of Helicobacter pylori, 15 pigs, 15 rabbits and 5 cows slaughtered for consumption were studied. Raised serum IgG levels were found in 93% of the pigs and 87% of the rabbits, but levels were normal in the cattle. In the controlled testings three of 22 humans had elevated IgG to H pylori and in all three H pylori was detected by the use of monoclonal antibody. Helicobacter pylori were identified in gastric brushings by a monoclonal antibody in 8 out of 10 pigs and 7 out of 10 rabbits. This study suggests an animal reservoir of Helicobacter pylori which may be of importance in human infection.

Animals↗

PubMed1990

Multielectrode cochlear implantation in children: the Quebec experience.

The Quebec Cochlear Implant Research Program has implanted three children since August 1987. This paper reports the results obtained with these children. All of them improved their auditory abilities with cochlear implantation and training. However, the abilities which spontaneously recovered following implantation, the speed of improvement, and the overall level of performance are different from one child to the other. Our data suggest that the age at onset of hearing loss, and possibly the number of years of deafness, may be related to the differences in performance.

Age Factors↗

PubMed1989

Cochlear implantation in Quebec city: auditory performance in a recently trained patient.

The Quebec Cochlear Implant Research Program has implanted nine patients since 1984. At the same time, we have been developing some original rehabilitative material for these French speaking patients. This paper reports the results obtained with our last adult patient. With his implant, J-P.F. has clearly improved his auditory response to sounds. After the training period, he demonstrated good abilities in detection, discrimination, identification and comprehension of sounds, phonemes, words and sentences. His lipreading has improved. The performance observed with this patient is comparable with the data reported in other studies using the same implant device.

Adult↗

PubMed1986

Comparative studies of Metarhizium anisopliae and Tolypocladium cylindrosporum as pathogens of mosquito larvae.

Mosquito fungal pathogens, Metarhizium anisopliae and Tolypocladium cylindrosporum, were compared with regard to virulence against the larvae of Aedes aegypti, Anopheles stephensi and Culex pipiens. Culex pipiens larvae were much more susceptible to M. anisopliae conidia than An. stephensi or Ae. aegypti. But Ae. aegypti and Cx. pipiens larvae were equally susceptible to T. cylindrosporum propagules which weakly attack An. stephensi. Using a high concentration conidial suspension (10(7) sp/ml) of M. anisopliae no. 139, Ae. aegypti larvae were killed immediately within 1.1 days, before intrahemocoelian invasion; but at lower concentrations (10(6) and 10(5) sp/ml), typical mycosis occurred. However, T. cylindrosporum no. 3 blastospores were much more pathogenic to Ae. aegypti larvae than conidia. Conidial suspension of 10(7) spores/ml killed 68% fourth-instar larvae, relative to the 96% invaded by blastospores under the same conditions. Presoaked conidia virulence appeared still intermediate between conidia and blastospores. At low temperatures, 15 degrees C, virulence of M. anisopliae highly decreased, while at the same temperature, T. cylindrosporum blastospores were still virulent.

Animals↗

PubMed1976

[Tympano-ossicular homografts].

Following a few European and American authors, we have undertaken tympano-ossicular homografts at the Hotel-Dieu de Quebec. The organization of the bank was achieved with many difficulties. We undertook our first surgical homografts in 1974, and 27 cases have since been performed. Our statistics are based on 19 cases. We obtained a perfect tympanic membrane in 17 cases, and 60 per cent of these have shown good improvement in hearing. This percentage is remarkable when one considers that we limited this procedure to cases for which all other techniques were bound to fail.

Audiometry↗

PubMedDate not supplied

[Development of auditory handicap after a multi-electrode cochlear implantation].

The efficacy of cochlear implantation as an aid to communication for profoundly hearing impaired persons is now established. International data show that some comprehension without visual cues is possible in many cases. Up to now, the bulk of research has been focused on psychoacoustical and speech perception measures. Hearing handicap changes following an implantation were rarely explored. On a longitudinal study on the benefits of cochlear implantation for twelve adults with profound acquired deafness, we explored the evolution of the hearing loss handicap. Two questionnaires were completed by the participants before and after implantation. A descriptive analysis of the data shows a rather moderate diminution of the handicap. The importance of the diminution appears inversely correlated to the length of deafness.

Adolescent↗