An even safer surgical environment.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to P G Bevan.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
We discuss a case of angiosarcoma of the spleen. Splenomegaly was discovered on a routine examination. At a later date it increased further in size and became painful. Peripheral smear and radio-isotope scannings suggested non-functioning spleen with haemorrhage within the tumour. Characteristic features of microangiopathic haemolysis, suggested in previous reports, was not found in our case.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The pathology, clinical features, diagnosis, and management of acute cholecystitis are outlined with reference to 311 cases out of a total of 631 patients treated for gallstones over a 15-year period. Operative procedures and the choice of antibiotics are discussed.
Explore the source record for details and available documents.
Forty-five patients with varying biliary pathology were injected with one gram of intramuscular cefazolin sodium prior to surgery. Serum, gallbladder bile, and common duct bile levels were measured. The type of biliary disease did not influence serum levels (mean, 29 mug per milliliter) which reached a peak one hour after injection. Mean common duct bile levels were reduced from 52 mug per milliliter in nonjaundiced patients to 4 mug per milliliter in those with jaundice (p less than 0.001). Patients with radiologically functioning gallbladders had significantly higher mean gallbladder bile levels (21 mug per milliliter; p less than 0.005). Surprisingly, the mean gallbladder bile level in acute cholecystitis was 25 mug per milliliter. As the minimum inhibitory concentration of cefazolin for organisms commonly found in the bile is 0.5 to 6 mug per milliliter, we suggest that cefazolin sodium may be of value in the treatment of biliary disease, particularly acute cholecystitis.
Explore the source record for details and available documents.
Explore the source record for details and available documents.