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Biomedical subjects

P G Contacos

Publications and source records attributed to P G Contacos.

At least 55 records · Page 3Linked to original sources
PubMed1972

Studies on the prophylactic and radical curative activity of RC-12 against Plasmodium cynomolgi in Macaca mulatta.

The compound 4-(2-bromo-4,5-dimethoxyphenyl)-1,1,7,7-tetraethyldiethylenetriamine (RC-12) has been shown to be active against the exoerythrocytic (EE) stages of the malaria parasite. Experiments on Plasmodium cynomolgi in rhesus monkeys showed that single weekly doses of 25 mg per kg of body weight would prevent the development and/or maturation of EE stages. The usefulness of RC-12 for effecting radical cures is, however, still open to doubt.

Animals↗
PubMed1970

Malaria therapy.

Explore the source record for details and available documents.

Drug Resistance, Microbial↗
PubMed1970

Primate malarias: man and monkeys.

The question whether malarias of animals could be considered true zoonoses was examined. The research in this connection for the past decade or so was reviewed. That simian malarias are true zoonoses has been adequately demonstrated. In addition, there is great potential for human malarias being true anthroponoses. The author considers, therefore, that the significance of non-human reservoirs of human malaria in the control or eradication of malaria should be reconsidered.

Animals↗
PubMed1969

Plasmodium malariae: transmission from monkey to man by mosquito bite.

Anopheles freeborni mosquitoes were infected by feeding on New World monkeys, Aotus trivirgatus, infected with a Nigerian strain of Plasmodium malariae. The infection was passed to human volunteers through the bites of these mosquitoes, demonstrating the practicability of using a simian host for infection of mosquitoes with a third species of human malaria parasite and of the use of such mosquitoes to transmit the infection from monkey to man.

Animals↗