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Biomedical subjects

P G Goddeeris

Publications and source records attributed to P G Goddeeris.

5 recordsLinked to original sources

Dilatation of the cystic veins in portal hypertension: sonographic demonstration.

High-resolution real-time ultrasound (6 MHz) demonstrated vascular dilatation in the adventitial layer of the gallbladder in 7 patients with portal hypertension. The hypertension was due to long-standing cirrhosis in 4 patients; the other 3 patients had prehepatic hypertension due to thrombosis involving the portal vein in 1 and the splenoportal confluence in 2. In one of the cirrhotic patients, postmortem correlation of sonographic, angiographic, and pathological findings showed that the dilated vessels seen on sonography were cystic veins draining normally into the portal vein rather than portosystemic anastomoses. This indicates that varicosity of the cystic vein can be associated with portal hypertension, taking the form of either passive dilatation or hepatopetal portal collateral circulation.

Dilatation, Pathologic↗

Gallbladder wall sonolucency in acute cholecystitis.

The usual ultrasound findings in acute cholecystitis include diffuse hyperreflective wall thickening, hazy wall delineation and gallbladder distension. In 11 patients with acute cholecystitis, an additional sign was seen consisting of a hyporeflective or sonolucent layer, continuous or interrupted, within the hyperreflective, thickened gallbladder wall. Anatomic-pathologic correlation, comparative CT scans and clinical follow-up studies showed subserosal edema and necrosis to be the most probable cause of this finding.

Acute Disease↗

Accuracy of endometrial biopsy dating in relation to the midcycle luteinizing hormone peak.

The accuracy of endometrial biopsy dating was evaluated in a selected group of apparently normal women in whom the basal body temperature (BBT), the onset of subsequent menstruation, the midcycle luteinizing hormone (LH) peak, and the 17beta-estradiol peak were determined. Forty-two women with regular cycles, normal ovaries at laparoscopy, and luteal phases of 12 to 15 days were studied. In group I (n=20), the infertility could be explained satisfactorily by either tubal occlusion or infertility of the husband, while in group II (n=22) no explanation was found for the infertility. In group I the duration of the luteal phase, defined as the interval between the LH peak and the onset of subsequent menstruation, was 13.4+/-0.7 days. The plasma 17beta-estradiol concentration declined (P less than 0.01) on the day of the LH peak in both groups of women, while the first significant rise (P less than 0.05) in BBT occurred in groups I and II, respectively, 1 and 2 days following the LH peak. Dating of the endometrial biopsy correlated with the LH peak with standard deviations of 1.2 and 1.3 days, respectively, in groups I and II. It is suggested that, in women with a progressive rise in BBT over several days, the localization of the LH peak can be helpful for correct interpretation of the endometrial biopsy.

Biopsy↗