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Biomedical subjects

P G Mann

Publications and source records attributed to P G Mann.

13 recordsLinked to original sources

Measles in monkeys: an epidemiological study.

This study describes aspects of measles in non-human primates. Monkeys infected before importation are shown to produce non-immune offspring in captivity in England. The high antibody titres found in most recently imported monkeys decline slowly during captivity in England. While measles is often fatal to monkeys, we have described an outbreak in which a number of symptomless infections occurred. Histological examination of fatal cases produced evidence of infection in the wall of the urinary bladder in one monkey. The close similarity between measles in humans and monkeys has been confirmed. It is considered that the study of infection among the latter may have significance for the former.

Animals

Introducing dietetics into general practice.

A dietetic clinic, initially monthly, now weekly, is held in a general medical practice with four partners. In one year 462 patients were seen (207 new and 255 repeat visits); 68% were on reducing diets and 8% were diabetics. Advice was given on a variety of therapeutic diets, ante-natal and infant feeding. The elderly were visited at home. Patients were pleased to have dietary advice available in general practice. Results of weight reductions have been encouraging. Prescriptions for appetite suppressants and laxatives have dropped.

Aged

Three-day and ten-day chemotherapy for urinary tract infections in general practice.

The length of a course of antibiotic treatment for urinary tract infection varies with the habits of the prescriber. Many patients do not complete a course of treatment once their symptoms have subsided. In uncomplicated urinary tract infection among women seen in general practice a three-day course of amoxycillin was as effective as a 10-day course of the same drug in the same dose. Relief of symptoms was equal in both groups and bacteriuria was eliminated equally successfully in both regimens. There was no significant difference between the two groups in the incidence of side effects from the drugs. The financial saving which could accrue from adopting this therapeutic regimen would be significant.

Amoxicillin

Bacteriuria in a Scottish island community. A comparison of chemical and cultural tests for bacteriuria applied in remote surroundings.

Four hundred and thirty-eight overtly healthy adults on Tiree were screened for bacteriuria by dip-inoculum culture and a tetrazolium reductase test.Dip-inoculum culture affords a simple and effective means of providing a service in quantitative urine bacteriology for communities remote from a laboratory.The pattern of bacteriuria on Tiree is much the same as in other communities surveyed. Criteria are discussed for assessing the sensitivity of the tetrazolium test in terms of quantitative urine culture.

Adult

Salmonellas on pig farms and in abattoirs.

Salmonella infection on two pig farms and its relation to infection in pigs at slaughter was studied. On the first farm feed ingredients were mixed on the farm, and these included fish meal which was found to be contaminated with salmonellas. The feed was pumped to pigs in liquid form. There was a high salmonella isolation rate at slaughter when the contaminated fish meal was fed in liquid feed, but it was significantly lower when no fish meal was fed to the pigs examined at slaughter. In some instances the same serotypes were found in fish meal and pig excreta on the farm and in caecal contents of the pigs at slaughter. No serotype was repeatedly isolated from any source and it appeared that the serotypes were not able to establish themselves in the pigs. It is concluded that infection found at slaughter originated on the farm where fish meal introduced and maintained infection. There was an opportunity for salmonellas to have multiplied in the liquid feed for several hours each day.On a second farm environmental conditions were similar, but feed was given in the form of ready-made pellets and nuts. Salmonellas were not isolated from the feed. At slaughter there was a significantly lower isolation rate than on the first farm.

Abattoirs