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Biomedical subjects

P Götell

Publications and source records attributed to P Götell.

11 recordsLinked to original sources
PubMed1993

The incidence of reflux oesophagitis. A study of endoscopy reports from a defined catchment area in Sweden.

Very few epidemiologic data on reflux oesophagitis are available. To estimate the incidence of reflux oesophagitis, all reports (n = 6733) of upper gastrointestinal endoscopy performed in patients aged > or = 16 years and living in a defined catchment area of 226,776 inhabitants were examined during a 2-year period. The incidence of reflux oesophagitis was calculated to be 120 per 100,000 inhabitants, and most of the incident cases (88%) were uncomplicated oesophagitis with single or multiple erosions. The incidence of complicated oesophagitis and Barrett's esophagus was 5.6 and 1.7 per 100,000, respectively. The mean age of all incident subjects was 56 +/- 18 years (range, 17-88 years) with a male to female ratio of 2:1. The severity of oesophagitis increased significantly with age (p = 0.0003), and most (75%) of the patients with complicated oesophagitis were > or = 60 years of age. Men had more severe grades of oesophagitis than women (p = 0.0003), and endoscopic evidence of peptic ulcer disease was observed in one of five patients.

Adolescent↗
PubMed1991

Coronary artery vasoregulation and left ventricular function in patients with angina pectoris-like pain and normal coronary angiograms.

Twenty patients with angina pectoris-like pain, normal coronary angiography and abnormal exercise 201Tl scans were investigated by means of haemodynamic, coronary sinus blood flow and lactate determinations before and after cold provocation, pacing and dipyridamole infusion. Radionuclide angiography, a new exercise 201Tl scan and noninvasive hyperventilation and ergonovine tests were performed. Intracoronary infusions of acetylcholine were given in increasing doses and a second coronary angiogram in combination with a 201Tl scintigram was performed. Despite a previously pathological 201Tl scintigram, with reversible perfusion defects, only ten of the patients had reversible perfusion defects at the second investigation. Hyperventilation and ergonovine tests did not result in ECG signs indicative of coronary spasm. Intracoronary infusion of acetylcholine resulted in a diffuse coronary constriction in 3 of 14 patients, and in one patient a perfusion defect was observed on thallium scintigram. In conclusion, although most of the common methods for inducing coronary vasospasm were used, no consistent pattern of reaction was found to explain the chest pains experienced in this group of patients.

Angina Pectoris↗