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Biomedical subjects

P Galian

Publications and source records attributed to P Galian.

At least 19 recordsLinked to original sources

[Isolated vesical localization of malignant B-cell lymphoma of low malignancy].

Primary malignant lymphoma of the bladder is infrequent and usually has a low malignancy, with a possibility of long-lasting remission. Our case is that of a 73-year-old woman who presented with a tumor of the bladder revealed by hematuria. She was treated with incomplete endoscopic resection, which showed that the lesion was a B cell lymphoma. After a complementary 60-Gy radiation therapy, remission was complete at 6 months. The histological and immunological study showed the lymphomatous proliferation infiltrating the chorion and the expression of the usual B-lymphocytic markers by the tumoral cells. Lymphoma of the bladder was described for the first time in 1885, and only a few small series of vesical lymphomas have been published since then. The prognosis is usually favorable owing to long-lasting remission. Complete surgical resection does not improve the results, and radiation therapy is the treatment of choice.

Aged

[Tubulo-papillary tumor of the kidney. Apropos of a case].

Tubulopapillary tumors represent a particular group of the renal tumors. Beyond their characteristic histological features, these tumors can be distinguished from the other renal tumors by the frequency of stage I on histology and by a more favorable prognosis.

Adenocarcinoma, Papillary

Gastric form of alpha chain disease.

A case of alpha chain disease, involving the stomach only, is reported in an Algerian man suffering from epigastric pains. Upper digestive tract fibreoptic endoscopy showed two antral ulcers and an ulcerative gastritis pattern, which promptly disappeared with cimetidine treatment. Antral biopsies at a distance from the ulcers, but not of the ulcer crater itself, disclosed a dense infiltration of antral lamina propria by mature or sometimes atypical plasma cells. On transmural surgical antral biopsy, the infiltrate spread to the superficial part of the submucosa. No other localisation of the disease was found in spite of multiple biopsies obtained by endoscopy, with a peroral capsule and during staging laparotomy. The alpha chain disease protein was absent from serum and urine, but found in the gastric juice and in the cytoplasma of the cellular infiltrate (alpha 1 subclass). A complete clinical, endoscopic, histological and immunological remission was observed after a six months' course of oral tetracycline.

Adult