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Biomedical subjects

P Galibert

Publications and source records attributed to P Galibert.

At least 19 recordsLinked to original sources

[Trans-oral approach. Technique and indications].

The trans-oral approach is a well codified and classical technique in neurosurgery. When correctly performed, this procedure gives excellent results in selected indications, such as: mechanical decompression of ondotoïdal vicious callus and more particularly, malformations of the craniovertebral function. This approach is also used for extirpation of C1, C2 and inferior clivus tumors. The complications of this technique are mainly septic, and must be prevented by appropriate pre and post-operative nursing.

Axis, Cervical Vertebra

[Percutaneous acrylic vertebroplasty as a treatment of vertebral angioma as well as painful and debilitating diseases].

Although vertebral hemangiomas are regarded as stable vascular malformations, a number of them progresses and may cause complications involving the cord or the nerve roots. In order to prevent this evolution, vertebral consolidation can be achieved with the percutaneous injection of acrylic cement into the angiomatous vertebra. The preventive effect of this procedure is often combined with relief from vertebral pain. This observation allowed extending the scope of application of this method to other painful spinal lesions such as osteoporosis and certain types of tumors.

Acrylates

[Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty].

Findings in several cases are used to demonstrate that certain vertebral angiomas may not be congenital and can ultimately provoke medullary or radicular neurologic complications. Radiotherapy is the usual treatment but is not always accepted unconditionally close to spinal cord. Destruction of angioma and consolidation of vertebral column can be obtained by percutaneous intrasomatic injection of acrylic cement. The preoperative radiologic examination includes direct phlebography with insertion of trocar, the vertebroplasty being performed under television screen surveillance. Results in seven patients treated are very encouraging but the current 2-year follow up requires extension. However, the method appears to be able to be included amongst treatment for an affection of sometimes seriously questioned benign nature.

Adult

[Multiple intracranial aneurysms. A very peculiar case of 8 sylvian aneurysms].

Reports vary with respect to frequency of multiple aneurysm but they are observed in an average of 13% of intracranial aneurysm cases. Multiple aneurysms generally involve several intracranial vascular trunks but those affecting the vertebrobasilar system and middle cerebral artery are the most common combinations. It is rare for more than two lesions to be located on the trunk of a same vessel. These data emphasize the exceptional nature of the clinical case presented. The eight aneurysms detected in this patient were all situated on the left sylvian artery and its proximal collaterals. Rupture of one of the aneurysms had provoked haemorrhage into sylvian fissure. All eight aneurysms were treated by eleven clamps during the course of a one-stage operation. Full recovery, with completely normal clinical and review arteriographic results, was obtained despite the postoperative onset of a right hemiplegia with aphasia.

Adult

[Intrasellar carotid aneurysm simulating prolactin adenoma].

A 52-year-old woman with secondary amenorrhea presented with ophthalmoplegia, subarachnoidal bleeding. Pituitary function tests showed mild hyperprolactinemia and deficiencies of other functions of adenohypophysis. X-ray films of the skull showed enlarged sella turcica, and CT scan was interpreted as demonstrating pituitary tumour. Carotid arteriography led to diagnosis of intrasellar aneurysm of the right internal carotid, without any pituitary tumour. After embolisation of the aneurysm, followed, by a temporo-sylvian anastomosis, endocrine functions did not improve. The mechanism of hyperprolactinemia is discussed, probably due to pituitary ischemia. This case provides evidence of interest of further investigations before a transsphenoidal surgery in pituitary tumours, in particular if subarachnoidal bleeding occurs.

Adenoma

[Primary empty sella turcica. Analysis of 14 cases and review of the literature].

14 patients (13 women, 1 man) presenting with primary empty sella had endocrinologic and radiological investigations. 8 women are obese, 5 multiparous. Initially, headaches have needed a radiological study of sella turcica in 8 cases (57%). Pneumoencephalography and/or CT scan have led to diagnosis; but in 3 cases, a suspected associated pituitary adenoma justified a surgical exploration. In one case, a GH-secreting microadenoma was found, in both other cases histologic studies revealed fibrous or normal pituitary. Endocrine findings were normal, regarding to gonadotrophs, corticotrophs and thyreotrophs. GH was blunted in four cases, below 5 ng/ml during insulin tolerance test. In 9 cases, GH rose to 19,51 +/- 10,03 ng/ml (mean +/- S.D.). In 13 patients, serum prolactin was normal: 7,1 +/- 3,9 ng/ml (normal values 2 -20 ng/ml), elevated in the last case: 112,5 ng/ml. One year later, two patients did not show any modification on clinical, radiological or endocrine data. Physiopathology of intrasellar arachnoidocele is discussed: intrasellar extension of subarachnoid space may be due to diaphragm insufficiency and disturbances of dynamics of cerebrospinal fluid, flattening the otherwise normal pituitary gland.

Adult

[Painful sciatic rubbing caused by benign synovioma of the spinal joints. Apropos of 4 cases].

Synovioma, a benign neoplasm arising from pigmented villonodular synovium or synovitis, is uncommon. It involves the tendons and joints of the finger, ankle and foot. In this study four cases of villonodular synovioma of spinal joints are reported. The authors studied 555 cases of patients operated for sciatica due to herniated disk. Histopathology showed that in four out of 555 cases sciatica was found to be due to synoviomas of the spinal joints. The patients, three women and one man, were between 54 and 70 years of age and each had had a long history of low back pain with episodes of sciatica. Clinical evaluation at the time of surgery showed moderate severity of signs and symptoms. Roentgenographic studies of all four cases revealed osteoarthritic changes of vertebral apophyses, with two cases of spondylolisthesis. The pathogenesis of synovioma remains controversial and its histopathological characterization -hyperplasia VS/true tumours- has not yet been determined. It is possible that the number of recorded cases of sciatica due to synoviomas is small because surgical and pathological studies in patients with sciatica associated with osteoarthritic changes have not been adequately performed. Surgery consists of a large resection of the capsule and ligament including resection of intraspinal extension. Because this study involves only four cases, the first of which occurred in 1977, the possibility of recurrence cannot be evaluated.

Aged

[Management of the non traumatic dissecting aneurysm of the cervical portion of the internal carotid artery (author's transl)].

The spontaneous dissecting aneurysms of the internal cervical carotid artery are renowned unusual, as about fifty cases only are reported in the literature. About 18 cases of dissecting aneurysms, 5 of which operated on and 13 clinically and radiologically followed, the authors try to draw a management. This one is resolutely conservative because: 1. It is possible to expect the spontaneous evolution according to the radiological form of the dissection which becomes in the great majority of cases toward repermeability. 2. The exceptional cases evolving to the thrombosis can later have an extra-intracranial anastomosis. 3. The cases justifying a direct surgical approach are exceptional and the operatory decision is easily taken according to the radiological aspect. On the whole, this pathology seems less unusual than the literature leads to suppose and the spontaneous evolution is worth to be well known because it conditions the management.

Adult

[Value of extra-intracranial anastomosis: based on a series of 65 cases].

The authors describe the results obtained in a series of 65 patients following extra-intracranial cortical anastomosis. The best indications for this procedure are transitory ischemic accidents which cannot be approached by the direct cervical route. Cases of prolonged or definitive vascular accidents and more especially localized lesions also gave valuable results but these depend upon the condition of the cerebral parenchyma which must be carefully evaluated.

Brain Ischemia