Diagnostic and prognostic applications of flow cytometry in pleuro-pulmonary neoplasms.
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Biomedical subjects
Publications and source records attributed to P Giacomelli.
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With the purpose of assessing the prevalence of dento-oro-facial parafunctions, an objective examination has been carried out of dental wear. At the same, a questionnaire on the parafunctional habits of a group of 108 patients suffering from cranio-mandibular disorders was distributed and a control sample of non-dysfunctional subjects of comparable age and sex features investigated. Data were collected by means of a special clinical record and an Individual Wear Index was worked out. The results showed a high presence of parafunctions in both groups, without significant differences. Dental wear was also comparable, showing, however, a precise age-proportional gradient. The facilitating structural causes, although confirming the decisive factor of muscular hyperactivity, were the loss of posterior support and deep bite. It was concluded that dysfunction and parafunction are not interdependent, although, evidently, they often coexist and are mutually aggravating.
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An open study was conducted in 40 randomized patients to evaluate the efficacy of ofloxacin in comparison with cefazolin in the treatment of acute, chronic and recurrent lower respiratory tract infections. The therapeutic efficacy of the two drugs was evaluated on the basis of bacteriological and clinical examinations. Bacteriological assays revealed that ofloxacin eliminated bacterial flora from sputum in 20/21 cases (14 Gram-negative and 7 Gram-positive), while cefazolin eradicated the pathogens in 12/19 cases (16 Gram-negative and 3 Gram-positive). In clinical terms, 20/21 (95.2%) infections were cured and 1/21 (4.8%) improved in the ofloxacin group as against 12/19 (63.2%) cured, 5/19 (26.3%) improved and 2/19 (10.5%) unchanged in the cefazolin group. The results of this study confirm the efficacy and excellent tolerance of ofloxacin in the treatment of lower respiratory tract infections.
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