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Biomedical subjects

P Gjøde

Publications and source records attributed to P Gjøde.

16 recordsLinked to original sources
PubMed1995

Randomized comparison of polyglycolic acid and polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing.

A randomized study of abdominal fascial closure using interrupted polyglyconate and polyglycolic acid sutures after laparotomy was carried out in 204 consecutive patients with suspected impaired wound healing. There were no statistically significant differences between the two sutures with regard to the development of fascial disruption and incisional hernia. Wound infection demanding surgical intervention was found in 7 per cent of patients with polyglyconate sutures and in 16 per cent of those with polyglycolic acid sutures (P = 0.04). Monofilament polyglyconate suture does not reduce the incidence of fascial disruption and incisional hernia after laparotomy in patients with suspected impaired wound healing but the incidence of wound infection may be reduced compared with that of multifilament polyglycolic acid suture.

Abdominal Muscles↗
PubMed1989

[Early resuturing after abdominal wound infection under prophylactic metronidazole and ampicillin].

A randomized double-blind investigation was undertaken to assess the effect of treatment with metronidazole and ampicillin in patients with subcutaneous wound infection after laparotomy and early resuture. The wounds were closed in the fourth day and the antibiotic cover lasted from one to four days. None of the patients developed signs of sepsis or new abscesses. All of the wounds healed primarily but there were slight defects in two patients. These did not require surgical treatment. It is concluded that early closure of infected wounds after laparotomy may be undertaken under metronidazole and ampicillin cover and that treatment for one day is sufficient.

Ampicillin↗
PubMed1989

Management of severe incisional abscesses following laparotomy. Early reclosure under cover of metronidazole and ampicillin.

Patients developing severe incisional abscesses following laparotomy were treated with incision and drainage followed by early reclosure under antibiotic cover with metronidazole and ampicillin anhydricum. Patients with subcutaneous abscesses were randomized into two groups that were treated with antibiotics for one day (n = 23) or four days (n = 27). These patients all underwent reclosure four days later. In a third group of patients (n = 14) abscesses had developed down to, but not through, the peritoneum. These patients received antibiotic treatment for four days and underwent reclosure a mean of 5 1/2 days later (range, four to eight days). No abscesses reappeared in any group and all wounds healed by first intention. Five patients healed totally, with minor defects, but there was no need for surgical intervention. We conclude that the early reclosure technique is a safe procedure under antibiotic cover with metronidazole and ampicillin. One day and four days of antibiotic treatment are equally safe in patients with subcutaneous abscesses.

Abscess↗
PubMed1988

Primary linitis plastica of the small bowel. Case report.

Linitis plastica carcinoma of the gastrointestinal tract is rare. No case with origin in the small intestine has been reported in the available literature. A 29-year-old man with vague abdominal symptoms and bilateral inguinal lymphadenopathy was found to have primary linitis plastica of the ileum. The prognosis is poor.

Adult↗
PubMed1987

The hydrodynamic consequences of transuretero-ureterostomia.

A transuretero-ureterostomy was performed in 8 pigs. In 4 pigs a non-dilated urinary tract was seen and pressure and electromyographic recordings showed that the procedure did not affect the electromyographic impulses in the recipient ureter. Impulses from the donor ureter were not transmitted to the common distal ureter. Two pigs died postoperatively from urinary leakage and two pigs developed stasis.

Anastomosis, Surgical↗
PubMed1987

Peroperative cefuroxime v. long-term ampicillin and metronidazole in high-risk biliary and gastric surgery. A multicentre trial.

Randomization to cefuroxime in a two-dose peroperative regimen or to combined peroperative and postoperative (4 days) ampicillin and metronidazole was performed in a series of 418 high-risk patients undergoing biliary or gastric surgery. Postoperative wound infection appeared in 9 of the 210 patients who received ampicillin and metronidazole and in 2 of the 208 given cefuroxime (p less than 0.05). Four intraabdominal abscesses occurred in the former group and one in the latter. Three of these abscesses probably were attributable to complications of surgery as such, leaving one intraabdominal abscess in each group. Peroperative cefuroxime is concluded to be more effective than longer administration of ampicillin/metronidazole as protection against wound infection in high-risk patients undergoing biliary or gastric surgery.

Adult↗
PubMed1982

Low dose rhesus immunoprophylaxis after early induced abortions.

A dose of 50 microgram anti-D immunoglobulin was administered as rhesus immunoprophylaxis following induced abortion performed by suction curettage before the thirteenth week of pregnancy in 463 consecutive patients. A feto-maternal blood loss of less than 2 ml was detected in 44 women (12%). After 6 months, a follow-up of 381 patients (82%) established that none of these patients was rhesus immunized with in vitro demonstrable antibodies. It is concluded that the low dose of anti-D administered is to be recommended for rhesus immunoprophylaxis after first trimester abortion.

Abortion, Induced↗
PubMed1980

Fetomaternal bleeding during attempts at external version.

The frequency and size of fetomaternal bleeds during the first attempt at external version of the fetus in breech presentation in 50 pregnant women were investigated. Fetomaternal bleeds of 0.1 to 1.5 ml were detected in 14 women (28 per cent). It is concluded that rhesus negative women should be given anti-D before attempts at external version are made.

Delivery, Obstetric↗
PubMedDate not supplied

Bactericidal antimicrobial cover in primary suture of perianal or pilonidal abscess. A prospective, randomized, double-blind clinical trial.

The effect of 1-day treatment vs. 4-day treatment with metronidazole and ampicillin in association with primary closure of perianal and pilonidal abscesses was evaluated in a double-blind clinical trial. The patients were randomly allocated to 1-day (group I) or 4-day (group II) antibiotic regimen. No clinical signs of sepsis appeared in any patient. Primary healing, without fistula formation was achieved in all 17 perianal abscesses in the 1-day therapy group and in 14 of 15 in the 4-day group (non-significant difference). Excision with primary suture of pilonidal abscess resulted in primary healing in 20 of 26 cases in group I and 20 of 30 in group II (non-significant difference). Healing with formation of a new sinus or secondary healing occurred in four and two cases, respectively, in the 1-day therapy group, and in two and nine of the 4-day group. One-day administration of metronidazole/ampicillin is as effective as 4-day treatment in primary closure of perianal and pilonidal abscess. The procedure appears to be safe in both groups, but more efficacious in perianal abscess.

Abscess↗