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Biomedical subjects

P Godoy

Publications and source records attributed to P Godoy.

At least 19 recordsLinked to original sources

[Tuberculous infection in schoolchildren of Les Borges Blanques].

The results of the study carried out with tuberculin skin test in primary school students from Les Borges Blanques are reported, so as to characterize the epidemiologic pattern of tuberculosis in this community. The overall prevalence of tuberculous infection was 3.6%. A 27.27% of the vaccinated and 2.32% of the nonvaccinated population, respectively, had a positive reaction. The prevalence of individuals vaccinated with BCG was 5.18%. The influence of vaccination on the PPD result was apparent. The incidence rates, excepting the 1981 cohort where it was 0, ranged from 0.61 (1976 cohort) and 1.01 (1978 cohort). The calculated RAI was 0.35%, with a yearly decline of infection of 29%. We emphasize the low yield of the investigation of contacts. Forty-three people living with 11 converters were investigated. No instance of active infection was found and only four of them were candidates to chemoprophylaxis.

Adolescent

[Yield of health exam in a rural school population].

The yield of the health status examination and associated factors in schoolchildren was assessed in the Primary Health Care center at Les Borges Blanques (Lérida), by means of the detection of abnormalities unknown by the parents receiving treatment. A self-administered questionnaire before the examination permitted to identify the already known abnormalities. Subsequently, a personal interview evaluated the follow-up. A total of 252 schoolchildren were evaluated, and 327 abnormalities were detected; 111 of these were unknown to the parents (33.94%); less than one half (48) presented for confirmation of the diagnosis. The diagnosis was confirmed in 44, treatment being prescribed in 36. In 33 schoolchildren (13.09%) the examination could have been useful. The observed low yield may be accounted for by the small rate of families that present for confirmation of the diagnosis. The personal communication of the diagnosis to the parents and the follow-up of cases might improve the yield.

Adolescent

Glomerulonephritis in Salmonella-Schistosoma mansoni association.

In 3 patients with Salmonella-Schistosoma mansoni association and clinical evidence of renal lesions, a percutaneous renal biopsy was performed. Renal function, assessed by endogenous creatinine clearance, was abnormal in 2 cases and serum levels of complement were decreased in all cases. Immune complex glomerulonephritis, evidenced by the presence of immunoglobulin and complement in the glomeruli was demonstrated in all cases. S. dublin and S. typhimurium antigens were found in the mesangium and in the capillary walls of 2 patients. After treatment with chloramphenicol, the S. mansoni infection persisted, but the clinical, laboratory, and immunopathological alterations were resolved. These findings suggest a direct role for Salmonella in the pathogenesis of glomerulonephritis described in patients with associated Salmonella and S. mansoni infections.

Adolescent

Intensive care unit treatment of acute renal failure following snake bite.

Twenty-nine patients with acute renal failure following bites by snakes of the genera Crotalus and Bothrops were treated in an Intensive Care Unit (ICU). Eight were given conservative treatment. Peritoneal dialysis was necessary in 21 patients, and hemodialysis in one of these. The main complications occurring while the patients were in the ICU were pulmonary edema (5 cases), respiratory failure (4), cardiac arrest (4), and hypovolemic shock (1 case). Three patients died with respiratory and hemodynamic disturbances while in the ICU, one of them during the polyuric phase. Twenty-four patients were discharged from the hospital with no clinical or laboratory evidence of renal failure. Two patients developed bilateral cortical necrosis of the kidney. One of them died in the general ward after interruption of dialysis and the other was discharged from the hospital with chronic renal failure. It was not possible to perform a kidney transplantation. The importance of the ICU in the recovery of such patients is stressed.

Acute Kidney Injury

Bilateral cortical necrosis and calcification of the kidneys following snakebite: a case report.

A 16 year-old-boy was admitted to the ICU of university hospital with acute renal failure following snakebite. The clinical evolution of the patient associated with radiological findings of renal calcification suggested bilateral cortical necrosis of the kidneys. The biopsy findings were compatible with this diagnosis. The patient was discharged 86 days after his admission, with chronic renal failure, since a kidney transplantation was not possible.

Acute Kidney Injury