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P Goebel

Publications and source records attributed to P Goebel.

31 records · Page 2Linked to original sources
PubMed1984

[A comparison of the psychosocial status of 125 abortion patients before and after the termination of pregnancy].

We described in a former study (Volume 3, 1982) the cases of 228 abortion patients, their psychosocial data and the conflicts from which the unwanted pregnancies, which are interrupted, arise. A follow-up study took place 18 to 24 months after the abortion. The crucial point of the follow-up investigation was the development of the relationship, newly wanted or unwanted pregnancies, the practice of contraception, the psychological coming to terms with the abortion as well as the re-evaluation of the conflict situations described in the earlier study. With these results we tried to understand the consequences of an abortion and to determine important parameters for the obligatory consultation prior to the abortion.

Abortion, Induced↗
PubMed1982

[The unwanted pregnancy--a neurotic conflict solving attempt? An analysis of the conflict situations of 228 abortion patients].

In the gynaecological department of a Berlin hospital 228 abortion patients were examined during a period of ten months. The examination consisted of a psychoanalytic survey, the answering of the Giessen-Test S and a questionnaire on stress. The patients had had permission for abortion and were hospitalized. The abortions were to be carried on the next day. The crucial point of the survey was to classify the psycho-social situation at the time of conception. Several typical conflict-situations were determined in which the "unwanted pregnancy" as a symptom had had the function of overcoming the actual neurotic conflicts. The typical conflict-situations and the corresponding functions are described.

Abortion, Induced↗
PubMed1979

[Vestibulo-ocular reactions by infants and young children (author's transl)].

Neurootological research demonstrated significantly different vestibulo-ocular reactions by infants and young children as compared to adults. Neurohistological research has demonstrated that the vestibular apparatus is developed by birth and therefore should be fully functional. Fifty full-term and healthy infants and children between 9 days and 24 months of age were placed on an electrically controlled rotating chair in order to determine the functional development of the vestibular system. The rotational test program consisted of a supraliminal acceleration stimulus of 3 degrees/s2, a constant rotation at 90 degrees/s for 3 minutes, and a final abrupt deceleration stimulus. The frequency and amplitude of the per- and post-rotatory nystagmus reaction were analysed from the electronystagmogram. The nystagmus frequencies demonstrate a low level in the first month. The per- and post-rotatory deviate clearly from each other in the following months. The amplitude values also start out low in the first month then climb thru the 7th month and finally stabilize or drop slightly in both the per- and post-rotatory phases. The accumulated results will be discussed and typical examples will be demonstrated.

Age Factors↗
PubMed1977

[Equilibriometric findings in partially blind and blind children (author's transl)].

26 of both blind or partially blind children were subjected to equilibriometric tests. By way of a vestibular-ocular test they were given the Rotatory-Intensity-Damping test. During the tests the per and postrotatory nystagmus reactions were electronystagmographicly registrated. For the vestibular-spinal tests the Unterberger's stepping test with photographic registration of the body-sway in the Cranio-Corpo-Gram was used. In most of the children you could identify a definite per and postrotatory reaction in spite of considerable spontaneous reactions. The strong eyelid movements of these patients, the intensive spontaneous deviations and diminished corneo-retinal potential made precise judgement of the electronystagmogram difficult. Comparison between the blind and partially blind children enabled the differences to be objectified. Blind-born children have a higher spontaneous activity, slightly diminished per and postrotatory nystagmus reactions and a diminished bodyequilibrium. These results can be explained on one side by habituation and on the other side by efferent structures, which have an inhibitory effect on the vestibular input.

Adolescent↗
PubMed1976

New plasmid-mediated nucleotidylation of aminoglycoside antibiotics in Staphlococcus aureus.

A wild-type strain of Staphylococcus aureus, which inactivates a wide variety of aminoglycosides (except the gentamicin components), has been found to harbor a plasmid (RAp01) that mediates the biosynthesis of a nucleotidyltransferase. This enzyme modifies the 4'-hydroxy function of these antibiotics. The plasmid has been studied, the enzyme responsible for this resistance pattern has been isolated by affinity chromatography, and its kinetics and physicochemistry have been characterized. The target of this enzyme has also been located by demonstrating the structure of one inactivated compound, 4'-(O)-adenylyltobramycin.

Aminoglycosides↗
PubMedDate not supplied

Molecular modeling of phytochrome using constitutive C-phycocyanin from Fremyella diplosiphon as a putative structural template.

Phytochrome, the ubiquitous photosensor in green plants, is similar to C-phycocyanin in a number of ways. We have produced a model of the phytochrome chromophore binding pocket based on the X-ray crystal structure of C-phycocyanin from Fremyella diplosiphon [Duerring et al. (1991) J. Mol. Biol. 217, 577-592]. Twenty residues around the chromophore binding site of C-phycocyanin were changed to the corresponding residues of Avena phytochrome A for the modeling. In the minimized model, Arg-318, Ala-319, the methylene of Ser-322, Leu-325, Gln-326, and Tyr-327 (using the numbering of the Avena sequence; Cys-323 is chromophore bound) form a pocket on one side of the chromophore. The other side of the chromophore lacks hydrogen-bond donors and is involved only in van der Waals contact with the chromophore. The overall structure of the model may be described as one peptide segment "anchoring" the chromophore hydrophobically, covalently, and electrostatically from several directions, while the other key peptide segment simply provides a hydrophobic surface for the chromophore to rest against. The red light absorbing (Pr) chromophore of the model is buried more deeply in the binding pocket than the far red light absorbing (Pfr) chromophore. This apparently reflects reduced compatibility of the chromophore with the pocket upon photoisomerization, which requires the insertion of hydrophilic parts of ring D into the hydrophobic core of the protein. This concept is consistent with the experimental evidence that photoisomerization of the Pr chromophore is followed by movement of the chromophore from its binding pocket. In the proposed model, increased exposure of hydrophobic portions of the Pfr chromophore compared to the Pr chromophore is consistent with the red shift observed in the first intermediate of the Pr to Pfr photoconversion. The proposed model may be tested by mutation experiments, thus providing a viable model to foster the current rapid progress of molecular biology in this field.

Amino Acid Sequence↗
PubMedDate not supplied

[The psychological and physical success of vasectomy reversal].

Forty men who had their vasectomy reversed were psychoanalitically examined. The changes of mind were above all concerned with the results of new relationships, initially no (more) children, then (more) children. The stability of the relationship at the time of vasectomy had been wrongly evaluated which must subsequently influence any advice given. Between 22 and 26 months after the reversal there was a telephone follow-up. Fertilization occurred with 32.1% of the cases, sperm was present in 77.4% (according to the men). The time between vasectomy and reversal was 4.8 years on average, the longest period being 8 years. A fertilization followed even when the anastomosis was only possible in one side in vas deferens area or on both sides in the caput area of the epididymis.

Fertility↗
PubMedDate not supplied

[Experience expressed in language and the function of metaphors].

On the assumption that psychoanalysis must also be speech analysis, the metaphoric manner of expression in connection with its underlying representations will be examined. It will be shown that in the metaphoric experience is linguistically revealed and accordingly experience plays a part in formation of speech. It will also be indicated that language helps to form the frame of experience and that society factors influence the use and formation of language. The connection will be stressed between illustrative and comparative language and the gaining of knowledge. The functions of the metaphor in the therapeutic process are be worked out and clarified with two case examples.

Humans↗