IVAC PCA pump.
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Analgesia, Patient-Controlled↗
Biomedical subjects
P Graziotti
Publications and source records attributed to P Graziotti.
[Conservative therapy of parenchymal renal carcinoma].
From January 1987 to October 1990, 20 patients (16 M. 4 F.) affect by localized renal cell carcinoma, underwent a conservative surgical treatment. This case study includes 8 patients with bilateral (4 synchronous-4 asynchronous), and 12 patients with unilateral renal carcinoma. In the latter group only two patients had a pathological contralateral kidney. A parenchyma sparing operation was performed electively in 10 cases and was necessary in the other 10. The tumors were found to be PT1 or pT2 in all the elective cases, except one unexpected pT3a; 1pT1, 5pT2, 1pT3a and 3pT3b in the remaining group. The follow up ranges between 1 and 36 months, two deaths in bilateral tumors cases were observed. No local recurrences have been detected up to now.
Adult↗
Extradural abscess following local anaesthetic and steroid injection for chronic low back pain.
A case is described of extradural abscess following extradural injection of local anaesthetic and steroid for the management of chronic low back pain. The common signs and symptoms are reviewed, possible causes discussed and the association with diabetes stressed.
Abscess↗
[Neoadjuvant chemotherapy of infiltrating carcinoma of the bladder: our experience].
From January 1987 until October 1989, 96 patients have been treated with radical cystectomy for locally advanced bladder cancer. Nineteen, out of 96 underwent chemotherapy (either M-VAC or M-VEC) before cystectomy. Five had T1G3 bladder tumor. After chemotherapy the results had been the following: 5 complete responses (CR) 26%, 7 partial responses (PR) (37%) and no changes in 7 patients (37%). During the first two courses of chemotherapy, 36 administrations out of 152 scheduled should have not been done because of drug toxicity. The seven patients who had no changes had a drug administration reduced of 41% with respect of a rate of reduction of 12% in the group of patients who had complete response. The urinary diversion after cystectomy were performed with a neobladder according to Reddy in 4 patients, with a colon conduit in 1 patient and with an ileal conduit in 12 patients. All the patients survived the surgery. We did not notice any difference in the follow up after surgery in those patients treated before cystectomy with chemotherapy with respect to the patients who underwent cystectomy without chemotherapy. Despite the fact that by now we can not state any conclusion about the efficacy of neoadiuvant chemotherapy, due both to the short follow up and to the small number of patients treated, we should however perform cystectomy in all the patients after chemotherapy because up to now we have no evidence that a conservative treatment of the bladder after chemotherapy could be safe.
Antineoplastic Combined Chemotherapy Protocols↗
[Conservative surgical treatment of renal carcinoma: presentation of a case of partial nephrectomy and autotransplantation].
The authors report a case of bench conservative renal surgery and autotransplantation, for adenocarcinoma in solitary kidney. Indications to a conservative treatment of renal cell carcinoma are described together with the technique to perform a bench surgery.
Adenocarcinoma↗
[An unusual case of entero-vesical fistula caused by a foreign body].
The authors describe a rare case of sigmoidovesical fistula due to a foreign body and giving trouble 30 years after the causative surgical procedure, namely an oopheroctomy. The cause of the fistula was apparently some suture material that had not been reabsorbed. Surgical excision of the fistula produced a complete recovery.
Castration↗
Spontaneous closure of vesicouterine fistula after cesarean section.
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Adult↗
[Treatment of renal carcinoma with metastases].
They stress the need to evaluate certain characteristic of the tumour metastasis in the light of a series of limit events pin-pointing the lack of understanding of the natural history of renal carcinoma. They stress the need to evaluate certain characteristic of the tumour which are not normally taken into consideration by the surgeon: rate of proliferation, monitoring of hormonal receptors, and immunological monitoring. They reach the conclusion that treatment of renal carcinoma with metastasis must be the outcome of multidisciplinary planning.
Antineoplastic Agents↗
[Surgery of the left renal vein (author's transl)].
The authors offer a review of surgical procedures involving the left renal vein and including some major manipulation (disobstruction, ligature, or change of connections), either as part of a planned operation or as an emergency measure. They stress the concept that the surgical trunk of the left renal vein can be ligated and cut with no permanent functional damage to the left kidney.
Adult↗