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Biomedical subjects

P Guacci

Publications and source records attributed to P Guacci.

5 recordsLinked to original sources

Trabeculectomy and extracapsular cataract extraction with posterior chamber lens implantation: a long term study.

Extracapsular cataract extraction with posterior chamber lens implantation and trabeculectomy was performed on 15 cataractous eyes in 15 patients: 5 were affected with chronic closed angle glaucoma and 10 with primary open angle glaucoma. This procedure offers the intraocular pressure control expected after trabeculectomy and, at the same time, gives the patients all visual benefits that cataract extraction with intraocular lens implantation warrants, without the introduction of new complications.

Aged↗

[Short-term comparison of the treatment of precocious puberty with 2 different LHRH antagonists (buserelin and long-acting triptorelin). An endocrinologic and echographic study].

To compare the short term effects of a short (Buserelin, 1800 micrograms/day as nasal spray) and a long acting (Triptorelin Depot, 3.75 mg/every 4 weeks i.m.) LHRH agonist, LH and FSH (LHRH test and 2 hours spontaneous rhythm during the morning and during the evening), estradiol and pelvic ultrasonography were evaluated in 12 children (1 boy, mean age 8.24 +/- 1.39 years, mean bone age 9.39 +/- 1.76 years) with early puberty before and after 1 and 2 months of treatment. Informed consent was obtained in all the cases. 6 patients started with Buserelin and 6 with Triptorelin. The therapeutic regimen was crossed over after 2 months of treatment and 2 more months of treatment withdrawal. The results indicate that while in both groups FSH values decreased significantly already from the last month of treatment, patients treated with Triptorelin showed a later LH decrease (significant only after 2 months of treatment). A decrease of pelvic structures volume was however evident only in patients treated with Triptorelin. After 2 months of treatment estradiol levels lowered (but not significantly) in both group. In conclusion despite a later LH decrement, patients treated with the long acting analogue showed however a more evident reduction of pelvic organs volume.

Buserelin↗

[Corticosteroid treatment regimes and growth hormone secretion in congenital adrenogenital syndrome].

11 patients with 21-hydroxylase deficiency were treated with three different corticosteroids and two different distributions of therapy during daytime. We found that: 1) a higher dose of steroid in the evening had a markedly inhibitory effect on nocturnal GH secretion; 2) of the steroids we used, dexamethasone caused the greatest reduction in nocturnal GH secretion; 3) in this study adrenal hormones seem less influenced by the different distribution of the corticosteroids during the 24 hours period.

Adolescent↗