[Effect of cholesterol on the tissue vitamin C content].
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Biomedical subjects
Publications and source records attributed to P Gutkowski.
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The effect of low-calcium diet and vitamin D-3 on acid-base balance in young rabbits. Acta Physiol. Pol. 1975, 26 (1): 103-108. The effect of secondary hyperparathyroidism and vitamin D-3 on the acid-base balance was investigated in young rabbits. No metabolic acidosis was found in animals given vitamin D-3 in addition to low-calcium diet.
In order to study the familial occurrence of bronchial hypereactivity (BH) the parents of infants with BH were evaluated. 47 pairs of parents of infants aged 10-33 months were studied. All infants following spastic bronchitis developed BH. All parents had bronchial reactivity assessed. All answered a questionnaire from which the following data were retrieved: family history, personal history, environmental data and smoking habits. A similar analysis was carried out on a group of 19 pairs of parents forming a control group, derived randomly from hospital personnel. In parents of children with BH a higher incidence of BH was found in comparison with the control chi 2 = 11.52; p less than 0.01). In 14 subjects a positive familial history was found. This did not differ from the control. The smoking habit was seen more often in the study group that in the control (chi 2 = 9.82; p less than 0.01). These results allow us to state that familial factors play a role in bronchial hypereactivity in early infancy.
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The respiratory pattern was evaluated in 32 newborn infants (21--premature infants). In 17 cases the cause of the respiratory insufficiency was the respiratory distress syndrome, in 15 pneumonias. Basing on registered spirograms the mean inspiratory time (Ti), the duration of the respiratory cycle (Ttot), time component (Ti/Ttot), respiratory frequency (f), normalized respiratory volume according to weight (Vt/kg) and Vt/Ti ratio were calculated. The authors did not find any differences in breathing pattern components between premature and at term infants nor between infants with RDS and pneumonias. In infants with RDS a shortened duration of inspiration was seen during the initial four days. Statistically significant differences were found in components of the respiratory pattern between studied and healthy infants.