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Biomedical subjects

P H Lange

Publications and source records attributed to P H Lange.

At least 19 recordsLinked to original sources
PubMed1992

Recurrent prostate cancer despite undetectable prostate specific antigen.

Serum prostate specific antigen (PSA) is a sensitive tumor marker following definitive therapy for adenocarcinoma of the prostate. Detectable levels of PSA after radical prostatectomy indicate residual and/or recurrent cancer. Therefore, we were surprised to document recurrent cancer following radical retropubic prostatectomy in a man who had undetectable serum PSA levels. This observation suggests that careful clinical monitoring remains essential after definitive therapy, since rare patients may have recurrent and/or residual carcinoma despite undetectable levels of PSA.

Adenocarcinoma↗
PubMed1979

Insertion of Gibbons ureteral stents using endourologic techniques.

We describe our technique for the antegrade insertion of the redesigned Gibbons ureteral stent. We have used this technique for 19 kidneys without failures or complications. The advantages of internal drainage and of antegrade stent placement are discussed.

Catheters, Indwelling↗
PubMed1979

Percutaneous U-loop nephrostomy.

Single-tube nephrostomy drainage can be converted to U-loop drainage using percutaneous methods. Because only local anesthesia is required the technique can be used for patients who are poor operative risks.

Humans↗
PubMed1979

Controlled ureteral meatotomy.

An endourologic technique for a safe and adequate ureteral meatotomy has been devised. The ureter is catheterized anterograde through a percutaneous nephrostomy and a controlled ureteral meatotomy is done with a modified ureteral catheter. A silicone splint is then placed. The technique is safer than other techniques because repeated, more proximal incisions can be made and because the splint and proximal urinary division will prevent extravasation.

Aged↗
PubMed1979

A comparison of the Small-Carrion and Scott-Bradley penile prostheses.

The Small-Carrion penile prosthesis has been implanted in 28 patients and the Scott-Bradley inflatable prosthesis has been implanted in 17. Almost all patients are satisfied with the results. There appeared to be no absolute correlation between the postoperative appearance of the penis and the sexual performance. Provided a reasonable cosmetic result is obtained the patient's attitude is the most important determinant of sexual function.

Consumer Behavior↗
PubMed1979

Immunologic testing of patients with genitourinary malignancies.

The discipline and techniques of immunology have been an important part of recent advances in genitourinary oncology. Although the initial promise of tumor immunology has not been realized in man, discoveries in the laboratory are revitalizing the expectation that this field will yet be of significant assistance in the diagnosis and treatment of cancer. Already tumor immunology studies along with new immunologic assay techniques have produced clinically important tumor markers, such as alpha-fetoprotein, human chorionic gonadotropin, and prostatic acid phosphatase, and have intensified the search for other markers. Finally, research activity is increasingly focusing on the tumor cell itself, again often using immunologic methods. Although most of this activity is still experimental, analysis of blood-group antigens in transitional cell carcinoma has produced sufficient data to suggest that such an approach will soon be a part of the urologist's clinical armamentarium in his efforts to treat patients with bladder tumors.

ABO Blood-Group System↗
PubMed1979

Deviation of the prostatic urethra in pelvic masses.

A cystourethrogram in the anteroposterior view can be useful for the diagnosis of a mass in the true pelvis in males, particularly when rectal examination is not possible. The technique is simple and rapid and has the same morbidity as simple urethral catheterization. This maneuver should be used whenever a pelvic mass is suspected in a male and physical findings fail to confirm its presence.

Adenocarcinoma↗
PubMed1978

Heterogeneity among human lymphocyte effector cells mediating spontaneous lymphocyte-mediated cytotoxicity.

The spontaneous lymphocyte-mediated cytotoxicity (SLMC) of lymphocytes from normal individuals was studied using the lymphocyte titration assay. Various techniques were used to study selectively several lymphocyte subpopulations. The activity of these subpopulations was tested in both the antibody-dependent cellular cytotoxicity (ADCC) and lymphocyte titration assays. Surface marker studies were performed on each lymphocyte subpopulation. The results from these studies indicate that effector cells mediating SLMC are a heterogeneous lymphocyte population composed of Fc-receptor-positive lymphocytes both with and without C3 receptors that consistently segregate with cells that do not form rosettes with sheep red blood cells. Our data suggest that, in many respects, the effector cells in SLMC and ADCC are identical. However, the mechanism appears to be different.

Adult↗
PubMed1978

Introduction of the Gibbons ureteral stent facilitated by antecedent percutaneous nephrostomy.

Patients in whom retrograde catheterization of the ureters has failed can have the Gibbons catheter placed by a new technique that requires no regional or general anesthesia. This technique entails antecedent percutaneous nephrostomy and passage of an angiographic catheter down the ureter. The catheterizing apparatus is attached to the angiographic catheter and then pulled into position.

Humans↗
PubMed1978

Extraction of ureteral calculi from patients with ileal loops: a new technique.

A technique is described by which calculi can be removed from the distal ureters of patients with ileal conduit urinary diversions. A percutaneous nephrostomy is done and an angiogram catheter is manipulated down the ureter past the obstruction. After the angiogram catheter is retrieved from the loop with a Bumpus forceps a stone basket is attached, pulled up the ureter and opened. The stone can then be captured under fluoroscopic control and, by replacing the stone basket with a silicone splint, the ureteroileostomy also can be splinted. This may be important particularly if there is extravasation from the ureteroileostomy after stone manipulation or operation.

Aged↗