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Biomedical subjects

P H Renton

Publications and source records attributed to P H Renton.

7 recordsLinked to original sources
PubMed1979

Lognormal distribution of HBsAg strengths in an English population.

The frequency distribution of reverse passive haemagglutination titres for HBsAg in the sera of 78 positive blood donors found furing 2.5-year period closely follows a lognormal distribution curve. This lognormal distribution suggests that the total population of HBsAg-positive donors during this period was approximately 84. The modified Hepatest now in use will be expected to detect 82 of these, and to miss only 1 HBsAg-positive donor in 50,000 screening tests of Manchester blood donors.

England↗
PubMed1977

Formaldehyde induced anti-N: a possible cause of renal graft failure.

Treatment of human red cells with low concentrations of formaldehyde induces an antigenic change which makes them react very strongly with the anti-N sera found in certain patients treated by haemodialysis. This supports the idea that formaldehyde sterilisation of reusable home dialysers leads to the development of anti-N in these patients' sera. The clinical problems produced by this antibody are discussed together with ways of overcoming them.

Antibody Formation↗