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Biomedical subjects

P Halliday

Publications and source records attributed to P Halliday.

11 recordsLinked to original sources

Patency of femorofemoral venous crossover grafts assessed by duplex scanning and phlebography.

This study was undertaken to determine the accuracy of duplex imaging of femorofemoral venous crossover grafts (Palma-Dale operation) for postthrombotic unilateral occlusion of the iliac vein. Twenty-four patients, 14 men and 10 women with a mean age of 50 years (range 24 to 72 years), were subjected to duplex imaging and phlebography a mean of 5 years after surgery. Scanning was done with patients in an erect position. A graft was reported as patient if it met the following criteria: it could be imaged in continuity, it could be compressed by the scan probe, and blood flow varied with respiration and was augmented by thigh compression on the symptomatic side. Phlebography indicated that 20 grafts were patent and 17 of these were correctly identified with duplex scanning. Three scans were false negative in obese patients in whom the graft could not be imaged. Four grafts, not imaged, were confirmed by phlebography to be occluded. Compared with phlebography, duplex scanning had a sensitivity of 85%, specificity of 100%, and overall accuracy of 88%. Duplex scanning is safe and accurate way to determine patency after femorofemoral venous bypass if the criteria for patency are fulfilled. If not, the true status of the graft must still be established by phlebography.

Adult

Subphrenic abscess: a study of 241 patients at the Royal Prince Edward Hospital, 1950-73.

A series of 241 patients with subphrenic abscess was analysed to seek reasons for the continuing mortality. Aspects of pathology, clinical presentation, special investigations and management were affected by therapy with broad spectrum antibiotics to make diagnosis more difficult, particularly in relation to left subphrenic abscesses. When transperitoneal exploration and drainage were employed, high morbidity and mortality resulted. Satisfactory results followed extraserous drainage. The introduction of parenteral hyperalimentation promised control fistulas associated with abscesses, a situation hitherto associated with a poor prognosis.

Adolescent

The surgical management of subphrenic abscess: a historical study.

This paper is a study of the evolution of the management of subphrenic abscess from the earliest reports to the present day. Its purpose is to compare and contrast the attitudes and practices established during the earlier years with those of the present, in particular in relation to changes consequent on the introduction of antibiotics.

Anti-Bacterial Agents

Development of the postthrombotic syndrome: its management at different stages.

The postthrombotic syndrome consists of clinical features which follow thrombosis of deep venous return of the limb. Patterns of postthrombotic changes remain difficult to predict and once established, difficult to contain and reverse. Following a thrombotic event of the lower limb, 3 clinical stages can be observed which may be followed by intervening quiescent intervals. Stage I, or the early phase, is characterized by the residual obstructive process following acute venous occlusion. This can be manifested by either a bursting type of pain (venous claudication) or edema of the leg. A thrombotic process can involve the calf veins, thigh veins, pelvic veins, or any combination of the three. Specific clinical syndromes develop depending on the venous pump system involved. The venous pump system consists of the plantar calf pump and the thigh pump. These serve to propel blood upward. Involvement of any one or more of the 3 in the thrombotic processes can result in a relative obstruction with a specific pattern of clinical symptoms. Optimally, the venous thrombotic process should be treated during this early phase to prevent the subsequent events which may render the process irreversible. The second stage of the postthrombotic syndrome consists of the development of fat sclerosis. At this stage, the process becomes progressively irreversible as the extravasation of fibrin into the interstitial space results in progressive fibrosis and sclerosis. This results in damage to the skin and subcutaneous tissues which render the process irreversible. Specific treatment, while still introducible at this stage, can halt the progress of the syndrome, but rarely results in complete reversal.(ABSTRACT TRUNCATED AT 250 WORDS)

Adipose Tissue